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Drinkable, Tough Hydrogels for Gastrointestinal Applications

Technology / Case number: #24642JQ
Giovanni Traverso / Robert Langer / Gary Liu / Matthew Pickett
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Fanzors are RNA-Guided Nucleases Encoded in Eukaryotic Genomes

Technology / Case number: #24942
Omar Abudayyeh / Jonathan S. Gootenberg / Justin Lim / Kaiyi Jiang
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Altered DNA Repair Pathway Engagement by Engineered CRISPR-Cas9 Nucleases

Technology / Case number: #23588
Vikash Pal Singh Chauhan / Robert Langer / Phillip Sharp
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Poly(-amino ester) Microparticles for Micronutrient Fortification

Technology / Case number: #22992
Ana Jaklenec / Robert Langer / Ruiqing Xiao / Linzixuan Rhoda Zhang
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Backbone Cleavable Polymethacrylates Via Optimized Thionolactone Comonoemers

Technology / Case number: #25292
Jeremiah A. Johnson / Kwangwook Ko
Technology Areas: Chemicals & Materials
Impact Areas: Sustainable Future, Advanced Materials
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Cavity-Enhanced Solid-State Nuclear Spin Gyroscope

Technology / Case number: #26298
Dirk R Englund / Matthew Trusheim / Hanfeng Wang
Technology Areas: Electronics & Photonics / Energy & Distribution / Sensing & Imaging
Impact Areas: Connected World
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Innate Immune Modulating RNA Vaccines

Technology / Case number: #26293H
B.j. Kim / Darrell J Irvine
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Liquid Exchange and Positioning of Cellular Entities in a Liquid-air Interface

Technology / Case number: #24928J
Linda Griffith / Georgios Katsikis / Haidong Feng / Joseph Doyle / Scott Manalis
Technology Areas: Biotechnology
Impact Areas: Healthy Living, Uncharted Frontiers
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Targeted Trans-splicing Using CRISPR-Cas Systems

Technology / Case number: #20505ER
Jacob Borrajo
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Smart Injection Needle System for Accurate Characterization of Cell Types, Concentrations, and Viability

Technology / Case number: #24367J
Giovanni Traverso / Fangzhou Xia / Kamal Youcef-Toumi / Adam Gierlach / Kewang Nan / Yiyuan Yang / Ming Zhao
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Polymer Film for BNL

Technology / Case number: #26245
Brian L Wardle / Carina Xiaochen Li / Yuying Lin / Robert Sansone
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Plk1 inhibitor and Microtubule Poison Dual Payload Antibody Drug Conjugates for the Treatment of Cancer

Technology / Case number: #26136
Jesse C Patterson / Michael Yaffe
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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System and Method for Enhancing Social Networks by Structural Modifications through Personalized Incentives

Technology / Case number: #15566TE
Yaniv Altshuler / Alex Paul Pentland
Technology Areas: Computer Science
Impact Areas: Connected World
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Transistor Structure and Method of Forming the Same

Technology / Case number: #25279
Tomas Palacios / Qingyun Xie / John Niroula / Pao-Chuan Shih / Gillian Micale
Technology Areas: Chemicals & Materials / Electronics & Photonics / Energy & Distribution
Impact Areas: Connected World
License

Branched Poly(-amino esters) for the Delivery of Nucleic Acids

Technology / Case number: #20333JQ
Giovanni Traverso / Yunhua Shi / Ameya Kirtane / Grace Junyue Zhong / Daniel Reker / Robert Langer / Hyunjoon Kim / Netra Rajesh / James Byrne / Gary Liu
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Amino Acid, Peptide, Polypeptide-Lipids (APPL) Derivatives and Uses Thereof

Technology / Case number: #14910Q
Kevin Love / Arturo Vegas / Delai Chen / Yi Chen / Yizhou Dong / Yunlong Zhang / Akinleye Alabi / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Composable Analytics

Technology / Case number: #16372L
Timothy Dasey / Micah Lee / Lars Fiedler / Ronald Locke / Kevin Nam / Rajendra Laad / Heather Griffin
Technology Areas: Computer Science
Impact Areas: Connected World
License

An Ultra-Wide-Band-Gap Semiconductor Optical Switch that is Capable of Fast Turn-Off and Achieves High Current Density with Visible Light at Low Irradiance

Technology / Case number: #26249
Rafael Jaramillo / Jiahao Dong
Technology Areas: Electronics & Photonics / Sensing & Imaging
Impact Areas: Advanced Materials
License

Patient-Specific Benchtop Beating Heart Simulator for Recreating Left Atrial Biomechanics and Hemodynamics for LAA Closure and HFpEF Intervention Testing

Technology / Case number: #25761
Ellen Roche / Keegan Mendez / Manisha Singh
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
License

A MEMS Based Encapsulated Hydrophone

Technology / Case number: #26013LJ
Daniel Freeman / Robert White / Jonathan Anderson / Georgios Karamanis / James Vlahakis
Technology Areas: Chemicals & Materials / Electronics & Photonics / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Sustainable Future, Connected World
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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