Karl Dane Wittrup

CP Dubbs Professor, Chemical Engr & Bioengineering
Department
Department of Chemical Engineering
Technology Areas
Drug Discovery and Research Tools: Antibodies, Genomics & Proteomics, Animal Models, Cell Interrogation, Cell Lines & Organoids / Therapeutics: Proteins & Antibodies, Vaccines, Small Molecules, Nucleic Acids, Cell Based Therapy / Biomaterials & Bioelectronics: Health Monitoring / Biotechnology: Sensors & Monitoring, Biomanufacturing, Synthetic Biology, DNA & RNA Editing / Chemicals & Materials: Nanotechnology & Nanomaterials, Metals / Diagnostics: Assays / Drug Delivery: Microparticles & Nanoparticles
Impact Areas
Healthy Living

Technologies

Versatile High Affinity Antibody to DOTA Chelates of Multiple Radionuclides

Exclusively Licensed Technology / Case number: #13506
Karl Dane Wittrup / Kelly Davis
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Alum Binding Proteins

Exclusively Licensed Technology, Tangible Property / Case number: #21571H
Darrell J Irvine / Yash Agarwal / Tyson Moyer / Karl Dane Wittrup
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living

METHODS FOR IDENTIFYING CHIMERIC ANTIGEN RECEPTOR-TARGETING LIGANDS AND USES THEREOF

Exclusively Licensed Technology / Case number: #22227H
Darrell J Irvine / Benjamin Cossette / Leyuan Ma / Naveen Mehta / Karl Dane Wittrup
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Collagen-Localized Immunomodulatory Molecules for Cancer Immunotherapy

Exclusively Licensed Technology / Case number: #20867
Karl Dane Wittrup / Magnolia Chinn / Allison Sheen / Joseph Palmeri / Noor Momin
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Synthetic Oncolytic LNP-Replicon RNA for Cancer Immunotherapy

Exclusively Licensed Technology / Case number: #21306HJQ
Darrell J Irvine / Noor Momin / Yingzhong Li / Yizhou Dong / Ron Weiss / Karl Dane Wittrup
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

An Amphiphilic Mimotope Vaccine to Enhance FDA-Approved Anti-CD19 CAR T Therapy

Exclusively Licensed Technology / Case number: #22096H
Darrell J Irvine / Benjamin Cossette / Leyuan Ma / Naveen Mehta / Karl Dane Wittrup
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Enhanced-Affinity Anti-ECM Nanobody-Cytokine Fusions and Their Applications

Exclusively Licensed Technology / Case number: #23602
Richard Hynes / Emi Lutz / Noor Momin / Noor Jailkhani / Karl Dane Wittrup
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Methods to Specifically Profile Protease Activity at Lymph Nodes

Technology / Case number: #18619H
Sangeeta Bhatia / Naveen Mehta / Jaideep Dudani / Andrew Warren / Karl Dane Wittrup / Darrell J Irvine
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
License

Single-Dose Combination Immunotherapy Augments Responses to Checkpoint Blockades for the Treatment of Cancer

Technology / Case number: #21150H
Darrell J Irvine / Chensu Wang / Karl Dane Wittrup
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Anti-Human KLRB1 Monoclonal Antibodies and Uses Thereof

Technology / Case number: #21645J
Karl Dane Wittrup / Nathan Mathewson / Byong Ha Kang / Kai Wucherpfennig
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

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