Collagen-Localized Immunomodulatory Molecules for Cancer Immunotherapy
Exclusively Licensed
Invention type: Technology
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Case number: #20867
The present disclosure provides immunomodulatory fusion proteins comprising a collagen-binding domain operably linked to an immunomodulatory domain. The disclosure also features compositions and methods of using the same, for example, to treat cancer.
Researchers
Karl Dane Wittrup
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Magnolia Chinn
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Allison Sheen
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Joseph Palmeri
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Noor Momin
Departments: Department of Chemical Engineering
Technology Areas: Biotechnology: Biomanufacturing, Synthetic Biology / Therapeutics: Proteins & Antibodies
Impact Areas: Healthy Living
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collagen-localized immunomodulatory molecules and methods thereof
Hong Kong | Published application -
collagen-localized immunomodulatory molecules and methods thereof
Singapore | Pending -
collagen-localized immunomodulatory molecules and methods thereof
United States of America | Pending -
collagen-localized immunomodulatory molecules and methods thereof
Japan | Granted | 7,557,882 -
collagen-localized immunomodulatory molecules and methods thereof
Canada | Published application -
collagen-localized immunomodulatory molecules and methods thereof
China | Published application -
collagen-localized immunomodulatory molecules and methods thereof
Australia | Granted | 2,019,346,335 -
collagen-localized immunomodulatory molecules and methods thereof
Brazil | Pending -
collagen-localized immunomodulatory molecules and methods thereof
Israel | Pending -
collagen-localized immunomodulatory molecules and methods thereof
India | Published application -
collagen-localized immunomodulatory molecules and methods thereof
Korea (south) | Published application -
collagen-localized immunomodulatory molecules and methods thereof
Singapore | Pending -
collagen-localized immunomodulatory molecules and methods thereof
European Patent Convention | Published application -
collagen-localized immunomodulatory molecules and methods thereof
Mexico | Pending -
collagen-localized immunomodulatory molecules and methods thereof
United States of America | Granted | 12,227,559
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