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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Oral Pill Water-Tight Payload Chamber Design with Triggerable Release

Technology / Case number: #25209J
Carlo Giovanni Traverso / Miguel Jimenez / James McRae / Emily Kolaya
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Methods and Apparatuses to Track Hand Configurations based on Ultrasound Signals

Technology / Case number: #25586
Xuanhe Zhao / Gengxi Lu
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science
Impact Areas: Healthy Living, Connected World
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Closed-Loop Noninvasive Brain Stimulation with Simultaneous Imaging to Control Cerebrospinal Fluid Flow in Humans

Technology / Case number: #25482
Laura Lewis / Joshua Levitt
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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A Microphysiological Model of the Brain Including Blood-brain Barrier, Neural Tissue and Meningeal Lymphatics

Technology / Case number: #24291
Roger Kamm
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Ingestible Electronics Integrated with Flexible Measurement Electrodes for Gastrointestinal Bioelectric Sensing

Technology / Case number: #23241
Carlo Giovanni Traverso / Robert Langer / Siheng You / So-Yoon Yang / Adam Gierlach / George Selsing
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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Inorganic Glass Composite Solid Electrolytes for Lithium or Sodium Batteries

Technology / Case number: #25304
Ju Li / Tao Dai
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Sustainable Future
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Bioelectronic Devices to Support Transplanted Cells in Vivo for Encapsulated Cell Therapies

Technology / Case number: #23269J
Suman Bose / Robert Langer / Siddharth Krishnan / Matthew Bochenek / Nima Khatib / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living
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Multisensory Gamma Stimulation Promotes Glymphatic Clearance of Amyloid

Technology / Case number: #25696PH
Li-Huei Tsai / Edward Boyden / Ping-Chieh Pao / Cheng-Yi Yang / Mitchell Murdock
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Software and Methods for Controlling Neural Responses in Deep Brain Regions

Technology / Case number: #20652M
James DiCarlo / Pouya Bashivan / Kohitij Kar
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science
Impact Areas: Healthy Living, Uncharted Frontiers
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Composite Anti-Fouling Coatings Designed via Full Spectral Hamaker Constant Minimization

Technology / Case number: #21606J
Michael Short / Max Carlson / Robert Simpson
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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NetCast: Low-Power Edge Computing with Optical Neural Networks via WDM Weight Broadcasting

Technology / Case number: #22737J
Dirk Englund / Ryan Hamerly
Technology Areas: Biotechnology / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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Chemical Compositions for Porous Lithium Anodes Enabling Coble Creep Mechanism in Solid State Electrolyte-Based Batteries with No Applied Stack Pressure

Technology / Case number: #23699J
Ju Li / Andrea Maurano / Yuming Chen / Ziqiang Wang / So Yeon Kim / Kai Pei
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Sustainable Future, Connected World
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A Fully Differential Piezoelectric Microphone and Amplifier System for Cochlear Implants and Other Hearing Devices

Technology / Case number: #23776JQ
Hideko Nakajima / Aaron Yeiser / Elizabeth Olson / Lukas Graf / Christopher McHugh / Ioannis Kymissis / Jeffrey Lang
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Adaptive, Integrated Mycotecture for Food, Composites and Mycoremediation

Technology / Case number: #24500X
Andreas Mershin
Technology Areas: Agriculture & Food / Chemicals & Materials
Impact Areas: Climate Stabilization
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Predictor of Deletions after Targeted Chromosome Cleavage

Technology / Case number: #21045
Max Shen / Jonathan Hsu / David Gifford
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living, Connected World
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A General Stress Patterning Method for Manufacturing Ultra-Precise Free-Form Deformation in Thin-Substrates

Technology / Case number: #21717
Youwei Yao / Brandon Chalifoux / Mark Schattenburg
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Optical Devices based on Phase Change Materials

Technology / Case number: #22247
Juejun Hu / Tian Gu / Yifei Zhang / Carlos Andres Rios Ocampo / Mikhail Shalaginov / Xiaoming Qiu
Technology Areas: Chemicals & Materials / Sensing & Imaging
Impact Areas: Advanced Materials
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Additively Manufactured Metal Matrix Composites

Technology / Case number: #24922
Ju Li / Alexander O'Brien / Emre Tekoglu
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Sustainable Future, Connected World
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A Novel Bio-Inspired Actuator Design

Technology / Case number: #24990
Daniela Rus / Chao Liu / Andrea Moncada / Hania Matusik / Deniz Erus
Technology Areas: Biotechnology / Industrial Engineering & Automation
Impact Areas: Connected World
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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