Hardware Models of Biochemical Reaction Networks

A system for modeling chemical reactions using analog or hybrid-analog-digital electronic circuits. The system exploits similarities between the kinetic rates of chemical reaction and the rates governing current flow in electronic devices such as bipolar junction transistors (BJTs) and metal oxide semiconductor field effect transistors (MOSFETs) operating at subthreshold conditions. These devices, which accurately model the stochastics of chemical processes, can be networked into large arrays to model chemical reaction networks, including biochemical reactions and genetic processes such as activation, induction, transcription, and translation.

Researchers

Rahul Sarpeshkar

Technology Areas: Biotechnology: Synthetic Biology / Computer Science: Bioinformatics
Impact Areas: Healthy Living

  • electronic system for modeling chemical reactions and biochemical processes
    United States of America | Granted | 8,285,523

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