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Structure-Guided Chemical Modification of Guide RNA and its Applications

Technology / Case number: #19175V
Hao Yin / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Crystalline and Amorphous Formulations Used to Deliver Anti-Fibrotic (and other) Compounds in Conjunction with Implanted Materials (Cells/Devices)

Technology / Case number: #18287J
Joshua Doloff / Shady Farah / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
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Thin-film Nanocomposite Membranes for Separating Ions and Uncharged Species in Water

Technology / Case number: #24335
Zachary Smith / Gang Han
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Ionizable Lipids for Messenger RNA Delivery

Technology, Tangible Property / Case number: #24861
Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Generalizable, High-Throughput Method to Rapidly add Chemical Moieties to a Small Molecule Library

Technology / Case number: #22196J
Angela Koehler / Brice Curtin / Jasmin Kruell / Catherine Henry / Sebastian Pomplun / Christina Woo / Chia-fu Chang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Printing Ferromagnetic Domains in Programmable Soft Materials to Achieve Untethered Fast Transformation

Technology / Case number: #20025
Xuanhe Zhao / Hyunwoo Yuk / Yoonho Kim
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Single Administration, Multi-Dose, Multi-Therapeutic Capable Delivery Platform for Veterinary Applications

Technology / Case number: #20943J
Carlo Giovanni Traverso / Alex Abramson / Ester Caffarel Salvador / Robert Langer / Christoph Winfried Johannes Steiger / Michael Williams / Jacob Coffey / Jason Li / Miguel Jimenez / Tiffany Hua
Technology Areas: Agriculture & Food / Biotechnology
Impact Areas: Healthy Living, Advanced Materials
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Cationic Lipidoids and Their Uses for Immunotherapy

Technology / Case number: #19803
Linxian Li / Yuxuan Huang / Lei Miao / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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A Catalytic Fluorination-Oxidation Cycle for the Conversion of Non-Pozzolanic Silica into Pozzolanic Silica

Technology / Case number: #24809
Camden Hunt / Jacqueline Prawira / Benjamin Mowbray / Yet-Ming Chiang
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Single-shot 16-fold Expansion Microscopy (16ExM)

Technology / Case number: #24859MH
Edward Boyden / Laura Kiessling / Tay Won Shin / Shiwei Wang / Yixi Liu / Harley Yoder
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Clockwise Learning Task

Technology / Case number: #25128M
Georgios Papageorgiou / Ann Graybiel
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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Engineered Synthetic IRES with Improved and Robust Translation in Circular RNA

Technology / Case number: #25300YJ
James Collins / Katherine Ilia / Shiva Razavi / Kehan Zhang / Xiaoyu Chen / Makoto Lalwani / Yu Li / Nayoung Kim
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Reconstituted Lipoprotein Particles to Rescue Lipid Defects in the Alzheimer's Brain

Technology / Case number: #25445P
Li-Huei Tsai / Rebecca Pinals
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Design of a Soft Robot for Missions In Small Diameter Water Pipelines

Technology, Tangible Property / Case number: #19144C
You Wu / Solene Demay / Kamal Youcef-Toumi
Technology Areas: Agriculture & Food / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Dual Electron/Lithium Ion Conductive Polymer Composite

Technology / Case number: #19054V
Michael McDonald / Paula Hammond
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Chemiresistive CO2 Sensor

Technology / Case number: #20865J
Bora Yoon / Gary Walsh / Timothy Swager
Technology Areas: Agriculture & Food / Chemicals & Materials
Impact Areas: Sustainable Future
Labels
  • CO2 Capture
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Ultra-High Resolution Mapping of 3D Genome Structure using Region Capture Micro-C

Technology / Case number: #24967
Anders Sejr Hansen / Viraat Goel / Miles Huseyin
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Optimized Alum-Anchored HIV Env Immunogens

Technology / Case number: #24972HJ
Kristen Rodrigues / Christopher Cottrell / Jon Steichen / William Schief / Darrell Irvine
Technology Areas: Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Electrostatically Actuated Deployable Space Structures

Technology / Case number: #24920
Zachary Cordero / Fabien Alain Christian Royer / John Zhang / Jeffrey Lang
Technology Areas: Chemicals & Materials / Communication Systems
Impact Areas: Uncharted Frontiers, Advanced Materials
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Liquid Metal Ejection 3D Printing

Technology / Case number: #21167
Justin Beroz / Ulrich Muecke / Henry Merrow / Caroline Jordan / Kaihao Zhang / Anastasios Hart
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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