In-Pipe Leak Detection System

In-pipe leak detection systems and related methods are disclosed for detecting in-pipe leaks while fluid is actively flowing through the pipe. The system can include a sensing element coupled to a membrane that are disposed parallel to or in-line with an axial direction of a fluid flow. The membrane is configured to be drawn into contact with the inner wall in response to a suction force caused by a leak. The leak is detected based on a transient output from the sensing element indicative of a stretch or strain on the membrane. The sensing element and the membrane is coupled to a support structure configured to position the membrane adjacent to an inner wall of a pipe. The support structure can include a mechanism that couples the membrane and the sensing element to the support structure and is configured to help in discriminating between leaks and false detections.