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RNA-based Logic Circuits with RNA Binding Proteins, Aptamers and Small Molecules

Exclusively Licensed Technology / Case number: #16631HJ
Darrell J Irvine / Kei Endo / Hirohide Saito / Tyler Wagner / Jacob Becraft / Katie Bodner / Tasuku Kitada / Velia Siciliano / Maria Hottelet Foley / Liliana Wroblewska / Ron Weiss
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Gene Editing by Cystolic Intracellular Delivery

Exclusively Licensed Technology / Case number: #17635J
Robert Langer / Alexandra Eyerman / Prashant Mali / Marc Lajoie / Armon Sharei / Klavs F. Jensen
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Enhancement of Peptide Antigenicity for T Cell Priming Using Albumin Binding Peptides

Exclusively Licensed Technology / Case number: #19388H
Darrell J Irvine / Rebecca Holden / Kelly Moynihan / Bradley L. Pentelute
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Method for Noninvasive Extraction of Fetal Cardiac Signals from Maternal Abdominal Recordings

Exclusively Licensed Technology / Case number: #13469J
Gari Clifford / Mohammed Shamsollahi / Christian Jutten / Reza Sameni
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living

Circulating Tumor Cell Isolation by Size Selective Tagging in a Microfluidic Device

Exclusively Licensed Technology / Case number: #16239
Robert Langer / Nahyun Cho / Viktor Adalsteinsson / Armon Sharei / J. Christopher Love / Klavs F. Jensen
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living

Activation Induced Clipping System

Technology / Case number: #24546J
Jianzhu Chen / Alaa Ali / Rizwan Romee / Guozhu Xie
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Microfabricated Biopolymer Scaffolds and Method of Making Same

Exclusively Licensed Technology / Case number: #11946J
Sangeeta Bhatia / Giovanni Vozzi / No Inventor
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

'Inverse Patterning' Process for 3D Multi-Compartmental Micro-Organization of Multiple Cell Types

Exclusively Licensed Technology / Case number: #15455H
Sangeeta Bhatia / Kelly Stevens
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

In Situ Sequencing of Expanded Biological Specimens

Non-Exclusively Licensed Technology / Case number: #17496TEYJQ
Edward Stuart Boyden / Shahar Alon / Evan Daugharthy / Adam Marblestone / Paul Tillberg / Fei Chen / George Church
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
License

Probing and Manipulating Cell Functions Through Intracellular Delivery

Exclusively Licensed Technology / Case number: #17162HJ
Robert Langer / Sophia Liu / Megan Heimann / George Hartoularos / Shirley Mao / Gregory Szeto / Armon Sharei / Ulrich Von Andrian / Pamela Basto / Siddharth Jhunjhunwala / Darrell J Irvine / Klavs F. Jensen
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

High-Throughput Platform for In-Vivo Sub-Cellular Screens on Vertebrate Larvae

Exclusively Licensed Technology / Case number: #14114
Mehmet Yanik / Cody Gilleland / Carlos Pardo Martin / Tsung-Yao Chang / Steven Charles Wasserman
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living

Stochastic Barcoding Method for Single-Cell Tracking

Exclusively Licensed Technology / Case number: #16514H
Darrell J Irvine / Marc Castellarnau / Gregory Szeto / J. Christopher Love / Joel Voldman
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Variable Interscan Time Analysis System

Exclusively Licensed Technology / Case number: #19459
James Fujimoto / Woo Jhon Choi / Stefan Ploner / Eric Moult
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living

Concepts and Devices for Electrokinetic Extraction and Delivery of Macromolecules for Intact Biological Systems

Exclusively Licensed Technology / Case number: #16669
Kwanghun Chung / Jae Cho / Evan Murray / Kimberly Ohn / Sung-Yon Kim
Technology Areas: Biotechnology
Impact Areas: Healthy Living

Tissue Fabrication by Selective Deletion within a Multicellular Construct

Exclusively Licensed Technology / Case number: #22098HJQ
Christopher Chen / Hyun Ho Song / Amanda Chen / Arnav Chhabra / Sangeeta Bhatia
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living

Arbitrary Targeted Deep Focused Neural Modulation

Non-Exclusively Licensed Technology / Case number: #17436TEQ
David Bono / Nir Grossman / Edward Stuart Boyden
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
License

A Fully Synthetic Nanoparticle Vaccine Platform Technology Composed of Dendrimer-Based Lipidoid Nanomaterials, Self-Amplifying Ribose Nucleic Acids and Polyethylene Glycol

Exclusively Licensed Technology / Case number: #17873WJH
Robert Langer / David Canner / Jasdave Chahal / Omar Khan / Daniel Anderson / Hidde Ploegh / Tyler Jacks
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Novel Classes of Channelrhodopsin

Exclusively Licensed Technology, Tangible Property / Case number: #15253TQJE
Gane Wong / Yongku Cho / Nathan Klapoetke / Edward Stuart Boyden / Brian Chow
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Rapid Solid Phase Peptide Synthesizer

Exclusively Licensed Technology / Case number: #15911
Klavs F. Jensen / Mark Simon / Bradley L. Pentelute / Patrick Heider / Andrea Adamo
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Expansion Microscopy for Tissue Using Post Expansion Immunostaining

Non-Exclusively Licensed Technology / Case number: #20914TE
Edward Stuart Boyden / Pablo Valdes Quevedo / Yongxin Zhao
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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