'Inverse Patterning' Process for 3D Multi-Compartmental Micro-Organization of Multiple Cell Types
Exclusively Licensed
Invention type: Technology
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Case number: #15455H
The invention features an “inverse patterning” or “Intaglio-Void/Embed-Relief Topographic (In VERT) molding” manufacturing process for generating high-resolution three-dimensional (3D) multi-cellular microstructures in distinct cellular compartments of a single hydrogel. The platform has general utility in the development of engineered tissues for human therapies, drug testing, and disease models. Additionally, the platform can serve as a model system for studying 3D cell-cell interactions in fields as diverse as stem cell biology to the development of cancer therapeutics.
Researchers
Sangeeta Bhatia
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Kelly Stevens
Departments: Health Sciences and Technology Program
Technology Areas: Biotechnology: Synthetic Biology, Tissue Engineering / Drug Discovery and Research Tools: Cell Culture
Impact Areas: Healthy Living
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inverse patterning process for three-deminsional multi-compartmental micro-organization of multiple cell types
United States of America | Granted | 10,072,257
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