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Dendrimer and Peptide Based Excipients for the Attenuation of Protein Aggregation

Technology / Case number: #14184
Bernhardt Trout
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation / Therapeutics
Impact Areas: Healthy Living
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Vaccine Targeting to Mucosal Lymphoid Tissues in the Gastrointestinal Tract

Technology / Case number: #25463H
Darrell J Irvine / Ozgun Kocabiyik
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Anti-Ebola Neutralizing Antibodies

Technology / Case number: #17334
Ram Sasisekharan / Devin Quinlan / Vidya Subramanian / Kannan Tharakaraman
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Artificially Engineered Protein Hydrogels to Mimic Nucleoporin Selective Gating

Technology / Case number: #17166
Bradley D. Olsen / Minkyu Kim
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Compositions for Protein Labeling Using Lipoic Acid Ligases

Technology / Case number: #15299J
Alice Ting / David Baker / Florian Richter / Lucas Nivon / Daniel Liu
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Phosphorylation-Based miRNA High Sensor

Technology / Case number: #19683
Ron Weiss / Ross Jones / Jin Huh
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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A Signal Inverter Module for RNA Cleavers: Detecting and Evaluating miRNA, Ribozymes, and Ribonucleases

Technology / Case number: #19604
Ron Weiss / Breanna DiAndreth
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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New Genetic Circuit Topologies for High Performance Multi-Input MicroRNA Sensors for Classifying Living Cell State

Technology / Case number: #19534
Ron Weiss / Jin Huh
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Optimized Opsin Trafficking with Fluorescence-Dead Protein Fusions

Technology / Case number: #18783TE
Edward Stuart Boyden / Demian Park / Aimei Yang / Kiryl Piatkevich
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Novel Method to Correct Altered Synaptic Signaling in Autism and Intellectual Disability

Technology / Case number: #18383PHJ
Mark Bear / Robert Lefkowitz / Laura Stoppel / Benjamin Auerbach
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Corynebacterium Probiotic to Prevent or Treat Cutaneous Staphylococcal Disease

Technology / Case number: #23721J
Tami Lieberman / Alexandra Poret / Victor Neel
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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TOX Inhibitor and Molecular Glue

Technology / Case number: #25241
Angela Koehler / Bocheng Wu
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Receptor Specific Peptides for Bcl-2 Family Anti-apoptotic Proteins

Technology / Case number: #20337J
Amy Keating / Jianfu Zhou / Vincent Xue / Justin Jenson / Gevorg Grigoryan
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Ingestible Electronic Pills for Hormone Modulation

Technology / Case number: #22427
Giovanni Traverso / James McRae / Khalil Ramadi
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Glucose-Responsive Glucagon Formulations for Closed-Loop Prophylactic Treatment of Hypoglycemia

Technology / Case number: #21838J
Robert Langer / Se Jun Lee / Jason Li / Giovanni Traverso
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Multi-stable Device Configurations and Controls for Gastric Drug Delivery Devices

Technology / Case number: #22017J
Robert Langer / Ludwig Erik Aguilar / Jens Laursen / Kuldeep Sanger / Nikolaj Eusebius Jakobsen / Adam Jun Bohr / Torben Sebastia Last / Yi Lu / Graham Arrick / Declan Gwynne / Jesper Windum / Brian Mouridsen / Jacob Wainer / Morten Frederiksen / Niclas Roxhed / Giovanni Traverso
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Anti-Zika Virus Antibodies

Technology / Case number: #18525J
Ram Sasisekharan / Subhash Vasudevan / Satoru Watanabe / Kuan Chan / Eng Ooi / Kannan Tharakaraman
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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User-Friendly and Easily-Accessible Synthetic Hydrogels for Biomaterials Application

Technology / Case number: #20694
Robert Langer / Marion Paolini / Jason Andresen / Owen Fenton
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Lipid Anchorage of Cytokines onto Layer-by-Layer Nanoparticles

Technology / Case number: #25070H
Darrell J Irvine / Ivan Pires / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Cell-Surface Anchored Cytokine Therapy

Technology, Tangible Property / Case number: #25245H
Darrell J Irvine / Luciano Santollani / Karl Dane Wittrup
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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