Device and Method for Maintaining Biliary Patency and Providing Local Chemotherapy in Pancreatic Cancer

Exclusively Licensed

Drug-eluting devices and methods for the treatment of tumors of the pancreas, biliary system, gallbladder, liver, small bowel, or colon, are provided. Methods include deploying a drug-eluting device having a film which includes a mixture of a degradable polymer and a chemotherapeutic drug, wherein the film has a thickness from about 2 µm to about 1000 µm, into a tissue site and releasing a therapeutically effective amount of the chemotherapeutic drug from the film to treat the tumor, wherein the release of the therapeutically effective amount of the drug from the film is controlled by in vivo degradation of the polymer at the tissue site.

Researchers

Elazer R Edelman / Christina Ferrone / Matteo Ligorio / David Ting / Jeffery Clark / Laura Indolfi / Robert Langer

Departments: Office of the Vice President for Research, Health Sciences and Technology Program, Office of the Institute Professors
Technology Areas: Biotechnology: Biomedical Devices & Systems / Chemicals & Materials: Composites, Polymers / Industrial Engineering & Automation: Manufacturing & Equipment
Impact Areas: Healthy Living

  • local drug delivery devices and methods for treating cancer
    United States of America | Published application
  • local drug delivery devices and methods for treating cancer
    Canada | Granted | 2,944,480
  • local drug delivery platform devices and methods for treating cancer
    European Patent Convention | Granted | 2,983,730
  • local drug delivery platform devices and methods for treating pancreatic cancer
    Japan | Granted | 6,431,528
  • local drug delivery platform devices and methods for treating cancer
    Japan | Published application
  • local drug delivery devices and methods for treating cancer
    United States of America | Granted | 11,167,066
  • local drug delivery devices and methods for treating cancer
    United States of America | Granted | 9,301,926
  • local drug delivery platform devices and methods for treating cancer
    United Kingdom | Granted | 2,983,730
  • local drug delivery platform devices and methods for treating cancer
    France | Granted | 2,983,730
  • local drug delivery platform devices and methods for treating cancer
    Italy | Granted | 2,983,730
  • local drug delivery platform devices and methods for treating cancer
    Germany | Granted | 2,983,730
  • local drug delivery platform devices and methods for treating cancer
    Spain | Granted | 2,983,730
  • local drug delivery devices and methods for treating cancer
    United States of America | Published application

License this technology

Interested in this technology? Connect with our experienced licensing team to initiate the process.

Sign up for technology updates

Sign up now to receive the latest updates on cutting-edge technologies and innovations.

More Technologies