Nanoparticle Delivery of Adjuvant-Method of Preparation and Uses Thereof

The present invention provides compositions and systems for delivery of nanocarriers to cells of the immune system. The invention provides nanocarriers capable of stimulating an immune response in T cells and/or in B cells. The invention provides nanocarriers that comprise an immunofeature surface having a plurality of nicotine moieties. The invention provides pharmaceutical compositions comprising inventive nanocarriers. The present invention provides methods of designing, manufacturing, and using inventive nanocarriers and pharmaceutical compositions thereof. For example, the present invention nanocarriers capable of eliciting an immune response and the production of anti-nicotine antibodies.

Researchers

Frank Alexis / Pamela Basto / Ulrich Von Andrian / Elliot Moseman / Matteo Iannacone / Jinjun Shi / Elena Tonti / Robert Langer / Omid Farokhzad

Departments: Office of the Institute Professors
Technology Areas: Drug Delivery: Microparticles & Nanoparticles / Therapeutics: Proteins & Antibodies
Impact Areas: Healthy Living

  • nicotine immunonanotherapeutics
    United States of America | Granted | 8,591,905
  • targeting of antigen presenting cells with immunonanotherapeutics
    United States of America | Granted | 8,343,497
  • targeting of antigen presenting cells with immunonanotherapeutics
    Korea (south) | Granted | 10
  • nicotine immunonanotherapeutics
    United States of America | Granted | 8,932,595
  • nicotine immunonanotherapeutics
    Israel | Granted | 212,244
  • targeting of antigen presenting cells with immunonanotherapeutics
    Israel | Granted | 212,245
  • targeting of antigen presenting cells with immunonanotherapeutics
    China | Granted | 102,245,199
  • targeting of antigen presenting cells with immunonanotherapeutics
    Mexico | Granted | 333,460
  • nicotine immunonanotherapeutics
    Mexico | Granted | 336,721
  • nicotine immunonanotherapeutics
    European Patent Convention | Granted | 2,346,528
  • targeting of antigen presenting cells with immunonanotherapeutics
    United States of America | Granted | 8,562,998
  • targeting of antigen presenting cells with immunonanotherapeutics
    European Patent Convention | Granted | 2,344,187
  • targeting of antigen presenting cells with immunonanotherapeutics
    United States of America | Granted | 9,308,280
  • nanoparticle delivery of adjuvant-method of preparation and uses thereof
    Liechtenstein | Granted | 2,346,528

License this technology

Interested in this technology? Connect with our experienced licensing team to initiate the process.

Sign up for technology updates

Sign up now to receive the latest updates on cutting-edge technologies and innovations.