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Method for High Efficiency in Vivo Gene Editing

Technology / Case number: #17117H
Wen Xue / Joseph Dorkin / Hao Yin / Tyler Jacks / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Programmable Drug Delivery Profiles of Tumor-Targeted Bacteria

Technology / Case number: #15818H
Tal Danino / Sangeeta Bhatia
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Split Peroxidases for Detection of Protein-Protein Interactions

Technology / Case number: #16082
Jeffrey Martell / Alice Ting
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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High-Throughput Screening Metabolic Flux Biosensor

Technology / Case number: #16813JW
Jose Avalos / Gregory Stephanopoulos / Gerald Fink
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Epigenetic Mechanisms Re-Establish Access to Long-Term Memory After Neuronal Loss

Technology / Case number: #12467HPBJ
Weiping Tang / Andre Fischer / Li-Huei Tsai / Stephen Haggarty / Stuart Schreiber
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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In Vivo Targeting of T-Cells with Antibody- and Cytokine Conjugated Liposomes

Technology / Case number: #16405H
Yiran Zheng / Yuan Zhang / Brandon Kwong / Darrell J Irvine
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Tough, Thermoreversible Hydrogels from the Arrested Phase Separation of Elastin-Like Polypeptides: Simple, Injectable, Biocompatible Substrates for the Engineering of Load-Bearing Tissues

Technology / Case number: #17430
Bradley D. Olsen / Matthew Glassman / Reginald Avery
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Chemotactic Magnetic Bead Chain Chemical Probe

Technology / Case number: #15619
Joshua Steimel / Alfredo Alexander-Katz / Hsieh Chen / Charles Sing
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Cystic Fibrosis Correction with Programmable Genomic Editing

Technology / Case number: #24666
Omar Abudayyeh / Jonathan S. Gootenberg / Matthew Yarnall / Christopher Fell
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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mRNA Subunit Vaccines for African Swine Fever

Technology / Case number: #25930
Junru Cui / Fangfeng Yuan / Jianzhu Chen
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Thermally-Gelling Injectable Hydrogel Composites for Therapeutic Delivery

Technology / Case number: #25878
Patrick Doyle / Talia Zheng
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Formulations for Stabilizing Lactobacillus and Bifidobacterium Strains

Technology / Case number: #25723J
Giovanni Traverso / Christina Karavasili / Matt Murphy / Samantha Bozorgzadeh / Mairead Heavey / Kimberley Biggs / Isaac Tucker
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Single-Walled Carbon Nano-Tube/Chitosan Hydrogel Array for the Label-Free, Optical Detection of Protein-Protein Interactions

Technology / Case number: #14201
Michael S. Strano / Jong Ho Kim / Paul Barone / Jin Ho Ahn / Nigel Reuel
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Compositions for Enhancing Esophageal Drug Retention and Absorption

Technology / Case number: #25238J
Giovanni Traverso / Christina Karavasili
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Synthesis and Anticancer Activity of Agelastatin Alkaloids

Technology / Case number: #16512J
Mo Movassaghi / Paul Hergenrother
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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Device for Trapping Hepatitis C Viral Particles in Ultra Low Concentrations

Technology / Case number: #14418J
Michael Cima / Christophoros Vassiliou / Vincent Liu / Gregory Ekchian / Hongye Ye / Christopher Wald / Sebastian Flacke / Fredric Gordon
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Diagnostics
Impact Areas: Healthy Living
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HDL Probe 2

Technology / Case number: #15787JR
Benito Munoz / Christopher Dockendorff / Miao Yu / Sivaraman Dandapani / Willmen Youngsaye / Partha Nag / Andrew Germain / Patrick Falloon / Monty Krieger / Thomas Nieland
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Porphyrin-based Sensors for Fluorescence and MRI

Technology / Case number: #12381
Xiao-An Zhang / Stephen J Lippard / Alan Pradip Jasanoff
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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The Site-Specific Incorporation of a Redox-Active and Chemically-Reactive Amino Acid into Proteins in E. Coli

Technology / Case number: #12973J
Peter Schultz / Jianming Xie / Mohammad Seyedsayamdost / Clement Tsz Chan / Lital Alfonta / JoAnne Stubbe
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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HDL Probe (BI-2012/024)

Technology / Case number: #15788JR
Benito Munoz / Miao Yu / Sivaraman Dandapani / Willmen Youngsaye / Partha Nag / Patrick Falloon / Chris Dockndorff / Timothy Lewis / Monty Krieger / Thomas Nieland
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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