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Natural Evolution of H5N1 Hemagglutinin Amino Acid Sequence and Its Implication on Human Adaptation and Antigenicity

Exclusively Licensed Technology / Case number: #16072
Rahul Raman / Nathan Stebbins / Kannan Tharakaraman / Karthik Viswanathan / Ram Sasisekharan
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living

Systems and Methods for Raman Spectroscopy of Chemical & Biological Species using Photonic Integrated Circuits

Exclusively Licensed Technology / Case number: #20503
Juejun Hu / Jerome Michon / Derek Kita
Technology Areas: Biotechnology / Diagnostics / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living

Large Field of View, Single Cell Detection System

Exclusively Licensed Technology / Case number: #13515J
Moungi G Bawendi / David Kirsch / W. David Lee / Lisa Marshall / Jorge Ferrer
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living

3-D Holographic Imaging Flow Cytometry

Non-Exclusively Licensed Technology / Case number: #16051
Ramachandra Dasari / Yongjin Sung / Niyom Lue / Zahid Yaqoob / Peter So
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Medical Treatment Applications of Swellable and Deformable Microspheres

Exclusively Licensed Technology / Case number: #14428J
Elazer R Edelman / Sujata Bhatia / Rinaldo Schiffino / Surbhi Mahajan / Garry Figuly / Tarek Shazly / Michael Feldstein
Technology Areas: Biomaterials & Bioelectronics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Method for Detecting Active and Latent Virally Infected Cells

Exclusively Licensed Technology / Case number: #13529
J. Christopher Love / Yuan Gong
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Barcoded Combinatorial Genetic Screening with CRISPR-CAS

Exclusively Licensed Technology / Case number: #17251
Timothy K Lu / Ching Gee (Gigi) Choi / Alan Siu Lun Wong
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

In Situ ATAC Sequencing

Non-Exclusively Licensed Technology / Case number: #19257TMEJQ
Edward Stuart Boyden / Paul Reginato / Jason Buenrostro / Andrew Payne / Shahar Alon / Fei Chen
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
License

Engineered Proteins for Targeted Full Spectrum Influenza Neutralization

Exclusively Licensed Technology / Case number: #13937
Ram Sasisekharan / Vidya Subramanian / Venkataramanan Soundararajan / Karthik Viswanathan / Sasisekharan Raguram / Viswanathan Sasisekharan
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Self Actuating Systems for Retention and Electrical Stimulation in the Gastrointestinal Tract

Technology / Case number: #20292JQ
Robert Langer / David Dellal / Ester Caffarel Salvador / Niclas Roxhed / Minsoo Khang / Alex Abramson / Taylor Bensel / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Solid Formulations with Ultra-High Drug Loading

Technology / Case number: #19446J
Robert Langer / Ester Caffarel Salvador / Niclas Roxhed / Minsoo Khang / Alex Abramson / Taylor Bensel / Giovanni Traverso
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Multi-Pronged Self-Orienting Millimeter-Scale Actuator for Drug Delivery

Technology / Case number: #21169JQ
Robert Langer / Jacob Wainer / Michael Williams / Alex Abramson / Giovanni Traverso
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Rare Earth Spatial/Spectral Barcodes for Multiplexed Biochemical Testing

Technology / Case number: #15231L
Patrick Doyle / Ji Seok Lee / Paul Bisso / Albert Swiston
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living, Advanced Materials
License

Self-Righting Systems, Methods, and Related Components

Technology / Case number: #20706JQ
Robert Langer / Ester Caffarel Salvador / Niclas Roxhed / Minsoo Khang / Alex Abramson / Taylor Bensel / Giovanni Traverso
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Using Gamma Wave Oscillation to Reduce Alzheimer's Pathology

Exclusively Licensed Technology / Case number: #18119P
Li-Huei Tsai / Chinnakkaruppan Adaikkan / Anthony Martorell / Hannah Iaccarino / Emery N Brown
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Biomimicry of Immune Tolerance for Universal Transplantation

Exclusively Licensed Technology / Case number: #20985HQJ
Sangeeta Bhatia / Marcela Maus / Arnav Chhabra
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Cyclin-Dependent Kinase 5 (Cdk5) Inhibitory Peptide

Technology / Case number: #19569P
Li-Huei Tsai / Jinsoo Seo
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Glycan-Binding Properties of the 2009 'Swine Flu' H1N1 Influenza A Virus Hemagglutinin and its Mutant Forms

Exclusively Licensed Technology / Case number: #13812
Rahul Raman / Akila Jayaraman / Karthik Viswanathan / Zachary Shriver / Ram Sasisekharan
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Micro Magnetic Resonance Relaxometry (µMRR) for Rapid and Non-Invasive Detection of Senescence in Mesenchymal Stem Cells

Exclusively Licensed Technology / Case number: #23566DE
Jongyoon Han / Ching Ann Tee / Shu Hui Neo / Smitha Surendran Thamarath / Laurie Boyer
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Methods for Expanding Clinical Tissue Specimens

Non-Exclusively Licensed Technology / Case number: #18384TEJ
Edward Stuart Boyden / Octavian Bucur / Andrew Beck / Yongxin Zhao
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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