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Rare Earth Spatial/Spectral Barcodes for Multiplexed Biochemical Testing

New
Technology / Case number: #15231L
Patrick Doyle / Albert Swiston / Paul Bisso / Ji Seok Lee
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living, Advanced Materials
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Fluidic-Based Cell Capture and Adhesion Measurement Concept

New
Technology / Case number: #25888
Bert Joannes C Vandereydt / Sean Parks / Domitille Avalle / Kripa K Varanasi
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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mRNA-based Myeloid Cell Stimulation Enhances Therapeutic Efficacy

New
Technology / Case number: #25731J
Ralph Weissleder / Akash Gupta / Kaelan Reed / Riddha Das / Christopher Garris / Daniel Anderson
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Altered DNA Repair Pathway Engagement by Engineered CRISPR-Cas9 Nucleases

Technology / Case number: #23588
Vikash Pal Singh Chauhan / Robert Langer / Phillip Sharp
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Poly(-amino ester) Microparticles for Micronutrient Fortification

Technology / Case number: #22992
Ana Jaklenec / Robert Langer / Ruiqing Xiao / Linzixuan Rhoda Zhang
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Method and Apparatus for High Throughput Diagnosis of Diseased Cells With Microchannel Devices

Technology / Case number: #11937
Ken Babcock / Subra Suresh / Scott Manalis / Thomas Burg
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
License

Plk1 inhibitor and Microtubule Poison Dual Payload Antibody Drug Conjugates for the Treatment of Cancer

Technology / Case number: #26136
Jesse C Patterson / Michael Yaffe
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Volume Contraction and Substrate Fluidization as a Means to Reduce Drag on Bodies Moving Through a Granular Substrate

Technology / Case number: #13498
Anette Hosoi / Amos Winter / Alexander Slocum
Technology Areas: Agriculture & Food / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Methods for Microbial Oil Overproduction from Cellulosic Materials

Technology / Case number: #15695
Mitchell Tai / Gregory Stephanopoulos
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Healthy Living, Sustainable Future
License

Expression Constructs for One-Step Construction of Allogeneic CAR-NK Cells

Technology, Tangible Property / Case number: #26118J
Rizwan Romee / Fuguo Liu / Jianzhu Chen
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Connected World
License

Methods for Improving Statistical Power in Genetic Discovery by Incorporating Quality Control Flags

Technology / Case number: #25839P
Manolis Kellis / Yosuke Tanigawa
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Reprogram the Genome of M13 Phage for Vaccination and Immunotherapy Applications

Technology / Case number: #25169
Shengnan Huang / Angela Belcher
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Using a Genetically Modified Human IPS Line to Screen for Drugs that Prevent or Treat Alzheimer's Disease

Technology / Case number: #26292P
Li-Huei Tsai / TaeHyun Kim / Leyla Akay / Matheus Victor / Masayuki Nakano
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Oxygenating Reservoir for Culture Media in Microphysiological Systems

Technology / Case number: #25858
Linda Griffith / Priyatanu Roy / Sydney Kim / Matthew Johnson / David L Trumper
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Discovery and Engineering of Novel Integrases for High-Efficiency Gene Integration

Technology / Case number: #23554
Omar Abudayyeh / Jonathan S. Gootenberg / Lukas Villiger / Justin Lim
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Programmable Addition Via Site-Specific Targeting Elements (PASTE)

Technology / Case number: #22225
Omar Abudayyeh / Jonathan S. Gootenberg
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Flow Cytometry with Mass Sensitive Readout

Technology / Case number: #12273J
Michel Godin / Ken Babcock / Scott Manalis / Thomas Burg
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
License

Raman Spectroscopy Based Sensitive and Specific Detection of Alternate Glycemic Markers, Glycated Hemoglobin (HbA1c) and Glycated Albumin for Longterm Diabetes Monitoring

Technology / Case number: #15295
Ishan Barman / Narahara Dingari / Jeon Woong Kang / Ramachandra Dasari
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
License

Multimodal and Network Phenotyping based on Single-Organelle In Situ Multiplexed Imaging

Technology / Case number: #25842
Mark Bathe / Reuven Falkovich
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Imidazole-Based Random Co-Polymer for Synthesis of Water Soluble Biocompatible Semiconductor Nanocrystals

Technology / Case number: #13877
Numpon Insin / Wenhao Liu / Peter Allen / Moungi G Bawendi
Technology Areas: Chemicals & Materials / Diagnostics / Electronics & Photonics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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