Reagents and Methods for Single-Molecule Peptide Sequencing

Exclusively Licensed

The present description provides methods, assays and reagents useful for sequencing proteins. Sequencing proteins in a broad sense involves observing the plausible identity and order of amino acids, which is useful for sequencing single polypeptide molecules or multiple molecules of a single polypeptide. In one aspect, the methods are useful for sequencing multiple polypeptides. The methods and reagents described herein can be useful for high resolution interrogation of the proteome and enabling ultrasensitive diagnostics critical for early detection of diseases.

Researchers

Edward Stuart Boyden / Alexi Choueiri / Daniel Estandian / Asmamaw Wassie

Departments: Department of Brain and Cognitive Sciences
Technology Areas: Biotechnology: Biomedical Devices & Systems, Synthetic Biology / Diagnostics: Assays / Drug Discovery and Research Tools: Genomics & Proteomics
Impact Areas: Healthy Living

  • single-molecule protein and peptide sequencing
    China | Granted | 0
  • single-molecule protein and peptide sequencing
    United States of America | Granted | 11,499,979
  • single-molecule protein and peptide sequencing
    Australia | Pending
  • single-molecule protein and peptide sequencing
    Japan | Published application
  • single-molecule protein and peptide sequencing
    United States of America | Published application
  • single-molecule protein and peptide sequencing
    China | Published application
  • single-molecule protein and peptide sequencing
    European Patent Convention | Published application
  • single-molecule protein and peptide sequencing
    Canada | Published application
  • single-molecule protein and peptide sequencing
    Australia | Granted | 2,024,203,694
  • single-molecule protein and peptide sequencing
    Hong Kong | Published application
  • single-molecule protein and peptide sequencing
    Australia | Granted | 2,020,206,321
  • single-molecule protein and peptide sequencing
    United States of America | Granted | 11,971,417
  • single-molecule protein and peptide sequencing
    Singapore | Pending

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