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Innate Immune Modulating RNA Vaccines

Technology / Case number: #26293H
Darrell J Irvine / B.j. Kim
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Multi-Dimensionally Encodable Neuron Device based on Two-Dimensional Materials

Technology / Case number: #25704J
Jeehwan Kim / Hyeongseok Jang / Min Kyu Song
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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AO mRNA-LNP Stabilization

Technology / Case number: #26266
Robert Langer / Tina Huang / Jooli Han / Linzixuan Rhoda Zhang / Ana Jaklenec
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Compact, Planar Transient Grating Spectroscopy System

Technology / Case number: #25473
Michael Short / Angus Wylie / Benjamin Dacus / Jonas Rajagopal
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living, Sustainable Future
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Optical Ising Machine and Optical Convolutional Neural Networks

Technology / Case number: #19700
Marin Soljacic / Hengameh Bagherianlemraski / Charles Roques-Carmes / Li Jing / Tena Dubcek Varga / Yichen Shen / Scott Skirlo
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Sensing & Imaging
Impact Areas: Connected World
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Prolonged-Release Hydrogel Formulations of Toll-Like Receptor Agonists for Intratumoral Injection to Increase Immunotherapy Response

Technology / Case number: #23215J
Robert Langer / Umar Mahmood / Eric Wehrenberg-Klee / Gabrielle Ndakwah / Jan-Georg Rosenboom / Avik Som / Arijit Basu / Giovanni Traverso
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Smart Injection Needle System for Accurate Characterization of Cell Types, Concentrations, and Viability

Technology / Case number: #24367J
Kamal Youcef-Toumi / Ming Zhao / Yiyuan Yang / Kewang Nan / Adam Gierlach / Fangzhou Xia / Giovanni Traverso
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Plk1 inhibitor and Microtubule Poison Dual Payload Antibody Drug Conjugates for the Treatment of Cancer

Technology / Case number: #26136
Michael Yaffe / Jesse C Patterson
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Lipid-Polymer Microparticles (mLPM) For Thermostable, Pulsatile mRNA-LNP Vaccines

Technology / Case number: #26154
Robert Langer / Yuting Huang / Linzixuan Rhoda Zhang / Ana Jaklenec
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Polymeric Core-Shell Particles for Pulsatile Release of HIV Vaccine

Technology / Case number: #26230
Robert Langer / Stacey Lin / Aki Gurram / Rishi Das / Amy Lee / Behnaz Eshaghi / Maria Kanelli / Ana Jaklenec
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Branched Poly(-amino esters) for the Delivery of Nucleic Acids

Technology / Case number: #20333JQ
Robert Langer / Gary Liu / James Byrne / Netra Kamat / Hyunjoon Kim / Daniel Reker / Grace Junyue Zhong / Ameya Kirtane / Yunhua Shi / Giovanni Traverso
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Amino Acid, Peptide, Polypeptide-Lipids (APPL) Derivatives and Uses Thereof

Technology / Case number: #14910Q
Robert Langer / Akinleye Alabi / Yunlong Zhang / Yizhou Dong / Yi Chen / Delai Chen / Arturo Vegas / Kevin Love / Daniel Anderson
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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An Ultra-Wide-Band-Gap Semiconductor Optical Switch that is Capable of Fast Turn-Off and Achieves High Current Density with Visible Light at Low Irradiance

Technology / Case number: #26249
Rafael Jaramillo / Jiahao Dong
Technology Areas: Electronics & Photonics / Sensing & Imaging
Impact Areas: Advanced Materials
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A MEMS Based Encapsulated Hydrophone

Technology / Case number: #26013LJ
Daniel Freeman / James Vlahakis / Georgios Karamanis / Jonathan Anderson / Robert White
Technology Areas: Chemicals & Materials / Electronics & Photonics / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Sustainable Future, Connected World
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Scale-Cascaded Coalescence

Technology / Case number: #15750L
Sai Ravela
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Sensing & Imaging
Impact Areas: Connected World
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Organic Indoor Location Discovery

Technology / Case number: #13472J
Seth Teller / James Hicks / Jonathan Ledlie / David Lambeth / Benjamin Charrow / Jonathan Battat / Dorothy Curtis
Technology Areas: Communication Systems / Sensing & Imaging
Impact Areas: Connected World
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Method to Improve the Image Quality of Positron Emission Tomography When Using Non-Standard Isotopes Based on Triple Coincidences

Technology / Case number: #16135
Shivang Dave / Joaquin Herraiz / Eduardo Lage / Vicente Parot
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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All-Optical Three-Dimensional Compression of Electron Pulses for Ultrafast Electron Imaging

Technology / Case number: #17343
Steven G Johnson / Byron Freelon / Timm Rohwer / Nuh Gedik / Liang Jie Wong
Technology Areas: Chemicals & Materials / Communication Systems / Sensing & Imaging
Impact Areas: Connected World, Advanced Materials
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Method for Quantitative Monitoring of In Vivo Tumor Oxygenation

Technology / Case number: #19207JQ
Michael Cima / Ehud Schmidt / Robert Cormack / Larissa Lee / Gregory Ekchian
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Reprogram the Genome of M13 Phage for Vaccination and Immunotherapy Applications

Technology / Case number: #25169
Angela Belcher / Shengnan Huang
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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