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Printable Programmable Machines: Origami Inspired Planar Fabrication of Three-Dimensional Systems

Technology / Case number: #15684J
Daniela Rus / Michael Tolley / Cagdas Onal / Robert Wood
Technology Areas: Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Using CRISPR/Cas9 to Encode Cellular History

Non-Exclusively Licensed Technology / Case number: #18025R
Alex Shalek / Alethe Gaillard de Saint Germain
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Genotype-Directed Local Delivery of Targeted Therapeutics at the Tumor Margin

Technology / Case number: #19863J
Robert Langer / Ganesh Shankar / Daniel Cahill / Ameya Kirtane / Giovanni Traverso
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Formulated, Biodegradable Polymeric Nanoparticles for Nucleic Acid Delivery to Non-Liver Targets

Technology / Case number: #19802
Daniel Anderson / Luke Rhym / Asha Patel / James Kaczmarek / Kevin Kauffman
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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High-Throughput Screens for Exploring Biological Functions of Microscale Biological Systems

Technology / Case number: #19737JR
Paul Blainey / Navpreet Ranu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Using over Wnt ing to Treat Colon Cancer: Small Molecule GSK3 Inhibitors and Novel Protein Isolation

Exclusively Licensed Technology / Case number: #23378JQ
George Eng / Jonathan Braverman / Omer Yilmaz
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Single-Cell RNA Sequencing Using Click-Chemistry

Technology / Case number: #20396
Phillip Sharp / Digbijay Mahat
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Diagnosis of Malignancy Using Developmental Relationships and Machine Learning

Technology / Case number: #23356
Salil Garg / Enrico Moiso
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Bioinspired Design of Self-Adjuvanted C3d-Fusion SARS-CoV-2 mRNA Vaccines

Technology / Case number: #23326
Robert Langer / Allen Jiang / Bowen Li / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Ingestible Chemical Energy Harvesting System with Extended Lifetime

Technology / Case number: #23174
Giovanni Traverso / So-Yoon Yang / Jason Li
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Engineering a Swine Macro-Organ Colorectal Cancer Platform to Combat Transport-Induced Chemotherapy Resistance

Technology / Case number: #22864JQ
Robert Langer / Daniel Reker / Vance Soares / Yunhua Shi / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
License

Closed-Loop Ingestible Robot for Radiation and Chemical Sensing

Technology / Case number: #22735
Giovanni Traverso / James Byrne / Hen Wei Huang
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
License

Ultra-high Efficiency Alcohol Engines Using Optimized Exhaust Heat Recovery

Technology / Case number: #15733K
Daniel Cohn / Leslie Bromberg
Technology Areas: Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Sustainable Future
License

Cellular Backpacks for Drug Delivery Across the Blood-Brain Barrier

Technology / Case number: #18547J
Robert Cohen / Natalya Klyachko / Yuling Zhao / Matthew Haney / Elena Batrakova / Roberta Polak / Michael F Rubner
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Pupil Engineering Method to Enhance the Signal of the Real-time non-invasive Particle Size Distribution Probe in Powders and During Mixing, Drying, Blending, and Milling Processes

Technology / Case number: #24521
George Barbastathis / Ajinkya Pandit / Zhen Guo / Qihang Zhang / Richard D Braatz / Allan S. Myerson
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Advanced Materials
License

Low-Temperature Synthesis of Two-Dimensional Materials

Technology / Case number: #24560
Jing Kong / Ji Hoon Park / Jiadi Zhu / Jiangtao Wang / Tomas Palacios
Technology Areas: Chemicals & Materials / Electronics & Photonics / Energy & Distribution / Industrial Engineering & Automation
Impact Areas: Advanced Materials
License

Robot Avatar

Technology / Case number: #24571
Harry Asada
Technology Areas: Communication Systems / Industrial Engineering & Automation
Impact Areas: Connected World
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Controller for Management of Optimal Schedules, used with Renewable-Energy Powered Irrigation Systems

Technology / Case number: #24578
Amos Winter / Simone Gelmini / Carolyn Sheline / Shane Pratt / Fiona Grant / Georgia Van de Zande
Technology Areas: Agriculture & Food / Environmental Engineering / Industrial Engineering & Automation
Impact Areas: Sustainable Future
License

Methods for Producing High-Level Squalene in Yarrowia Lipolytica

Exclusively Licensed Technology / Case number: #24579
Gregory Stephanopoulos / Yongshuo Ma
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

3D-Printed Field Emission Sources for Compact Systems

Technology / Case number: #21454J
Luis Fernando Velasquez-Garcia / Imperio Perales Martinez
Technology Areas: Chemicals & Materials / Electronics & Photonics / Industrial Engineering & Automation
Impact Areas: Advanced Materials
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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