Intravesical Drug Delivery Device with a Retention Feature

Exclusively Licensed

An implantable medical device is provided for controlled drug delivery within the bladder, or other body vesicle. The device may include at least one drug reservoir component comprising a drug; and a vesicle retention frame which comprises an elastic wire having a first end, an opposing second end, and an intermediate region therebetween, wherein the drug reservoir component is attached to the intermediate region of the vesicle retention frame. The retention frame prevents accidental voiding of the device from the bladder, and it preferably has a spring constant selected for the device to effectively stay in the bladder during urination while minimizing the irritation of the bladder.

Researchers

Michael Cima / Heejin Lee

Departments: Department of Materials Science and Engineering
Technology Areas: Biotechnology: Biomedical Devices & Systems / Drug Delivery: Microparticles & Nanoparticles
Impact Areas: Healthy Living

  • intravesical drug delivery devices
    United States of America | Granted | 12,296,127
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    United States of America | Granted | 9,586,035
  • intravesical drug delivery device with a retention feature
    Hong Kong | Granted | 0
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Australia | Granted | 2,008,335,077
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Brazil | Granted | 0
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Canada | Granted | 2,706,384
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    China | Granted | 200,880,120,352
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    India | Granted | 315,921
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Israel | Granted | 205,960
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Japan | Granted | 5,560,200
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Korea (south) | Granted | 10
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Mexico | Granted | 348,005
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    New Zealand | Granted | 585,449
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Singapore | Granted | 162,090
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    South Africa | Granted | 2,010
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Viet Nam | Granted | 22,041
  • intravesical drug delivery methods and devices
    United States of America | Granted | 10,646,691
  • intravesical drug delivery devices
    United States of America | Granted | 11,612,718
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Switzerland | Granted | 2,231,254
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Denmark | Granted | 2,231,254
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Finland | Granted | 2,231,254
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    France | Granted | 2,231,254
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Hungary | Granted | 0
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Ireland | Granted | 2,231,254
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Italy | Granted | 2,231,254
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Netherlands | Granted | 2,231,254
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Poland | Granted | 2,231,254
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Spain | Granted | 2,231,254
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Sweden | Granted | 2,231,254
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Turkey | Granted | 2,231,254
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    United Kingdom | Granted | 2,231,254
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Austria | Granted | 2,231,254
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Belgium | Granted | 2,231,254
  • implantable drug delivery device and methods for treatment of the bladder and other body vesicles or lumens
    Germany | Granted | 2,231,254

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