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Machine Learned Chemical Intuition for the AI Generation of Molecules within Specific Chemical Spaces

Technology / Case number: #26403
Brett McGuire / Zachary Fried
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Oxygen-Generating Scaffolds for Stem Cell Depot Support

Technology / Case number: #24650J
Giovanni Traverso / Young-Geun Park
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Emulsion Agglutination Assay for Sensing of Zika Virus

Technology / Case number: #20574Q
Timothy Manning Swager / Kosuke Yoshinaga / Ki-Joo Sung / Lukas Zeininger / Eric Miller / Qifan Zhang / Hadley Sikes
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Seqwell Ancillary Tools and Assays Including StimSeq and Spatial Barcoding

Technology / Case number: #19508
J. Christopher Love / Marc Wadsworth / Travis Hughes / Alex Shalek / Todd Gierahn
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Methods, Procedures, and Material Compositions to Formulate Thermally Stable Solid-State Lipid Nanoparticles via Drying at Ambient Conditions

Technology / Case number: #26177
Robert Langer / Amy Lee / Khanh Tran / Jinbi Tian / Mina Konakovic Lukovic / Ana Jaklenec
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Poly(-amino ester) Microparticles for Micronutrient Fortification

Technology / Case number: #22992
Robert Langer / Linzixuan Rhoda Zhang / Ruiqing Xiao / Ana Jaklenec
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Altered DNA Repair Pathway Engagement by Engineered CRISPR-Cas9 Nucleases

Technology / Case number: #23588
Robert Langer / Vikash Pal Singh Chauhan / Phillip Sharp
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Compacted Powder Needles for Intramucosal Delivery

Technology / Case number: #21149QJ
Giovanni Traverso / Morten Frederiksen
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
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Automated Flow Synthesis of Combinatorial Protein Libraries

Technology / Case number: #26382J
Bradley L. Pentelute / Dimuthu Vithanage / Corey Johnson / John Albin / Gha Young Lee / Wayne Vuong
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Silicone Valve API Compartment Sealing Barrier

Technology / Case number: #21569QJ
Giovanni Traverso / Brian Jensen / Mikkel Oliver Jespersen / Morten Frederiksen / Alex Abramson
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Spring-Loaded Double Pentograph (SLDP) Mechanism for Human Balancing and Weight Support

Technology / Case number: #25811
Harry Asada / Ravi Tejwani
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Innate Immune Modulating RNA Vaccines

Technology / Case number: #26293H
Darrell J Irvine / B.j. Kim
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Method and Apparatus for High Throughput Diagnosis of Diseased Cells With Microchannel Devices

Technology / Case number: #11937
Subra Suresh / Ken Babcock / Thomas Burg / Scott Manalis
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Multi-Dimensionally Encodable Neuron Device based on Two-Dimensional Materials

Technology / Case number: #25704J
Jeehwan Kim / Hyeongseok Jang / Min Kyu Song
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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AO mRNA-LNP Stabilization

Technology / Case number: #26266
Robert Langer / Tina Huang / Jooli Han / Linzixuan Rhoda Zhang / Ana Jaklenec
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Compact, Planar Transient Grating Spectroscopy System

Technology / Case number: #25473
Michael Short / Angus Wylie / Benjamin Dacus / Jonas Rajagopal
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living, Sustainable Future
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Prolonged-Release Hydrogel Formulations of Toll-Like Receptor Agonists for Intratumoral Injection to Increase Immunotherapy Response

Technology / Case number: #23215J
Robert Langer / Umar Mahmood / Eric Wehrenberg-Klee / Gabrielle Ndakwah / Jan-Georg Rosenboom / Avik Som / Arijit Basu / Giovanni Traverso
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Liquid Exchange and Positioning of Cellular Entities in a Liquid-air Interface

Technology / Case number: #24928J
Linda Griffith / Joseph Doyle / Haidong Feng / Georgios Katsikis / Scott Manalis
Technology Areas: Biotechnology
Impact Areas: Healthy Living, Uncharted Frontiers
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  • Women's Health
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Smart Injection Needle System for Accurate Characterization of Cell Types, Concentrations, and Viability

Technology / Case number: #24367J
Kamal Youcef-Toumi / Ming Zhao / Yiyuan Yang / Kewang Nan / Adam Gierlach / Fangzhou Xia / Giovanni Traverso
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Plk1 inhibitor and Microtubule Poison Dual Payload Antibody Drug Conjugates for the Treatment of Cancer

Technology / Case number: #26136
Michael Yaffe / Jesse C Patterson
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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