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Human Step Following

Non-Exclusively Licensed Technology / Case number: #17856
Harry Asada / Kosuke Takeuchi
Technology Areas: Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Healthy Living
License

Protein for Rapid, Efficient Capture of Tuberculosis Antigens from Urine

Non-Exclusively Licensed Technology / Case number: #19946
Hadley Sikes / Ki-Joo Sung / Eric Miller
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
License

Specific Viral Targeting of Hematopoietic Stem Cells via Engineering of Viral Tropism

Exclusively Licensed Technology / Case number: #22988JQ
Michael Birnbaum / Cassandra Burnett / Kole Roybal / Stephanie Gaglione / Connor Dobson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Composition of an Array of Microwells with an Integrated Microfluidic System

Exclusively Licensed Technology / Case number: #13627
J. Christopher Love / Eliseo Papa / Craig Story
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Tumor-Specific CAR-T Cell Therapy for Treating Acute Myeloid Leukemia

Exclusively Licensed Technology / Case number: #21827
Jianzhu Chen / Guozhu Xie
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Low Temperature Crosslinking of Biodegradable Elastomers

Exclusively Licensed Technology / Case number: #11796
Robert Langer / Joost Bruggeman / Christiaan Nijst / Lino da Silva Ferreira / Jeffrey Michael Karp / Sonia Takasaki (Kim) / Jason Burdick / Christopher Bettinger / Andreas Zumbuehl
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

Single-Site-Specific Cysteine Arylation Directed by A Genetically Encodable Pi-Clamp

Exclusively Licensed Technology / Case number: #16898
Bradley L. Pentelute / Peng Dai / Chi Zhang
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Combined Inhibition of Polo-like kinase 1 (Plk1) and Microtubule Polymerization for the Treatment of Cancer

Exclusively Licensed Technology / Case number: #21961
Michael Yaffe / Jesse C Patterson / Brian A Joughin
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

METHODS FOR IDENTIFYING CHIMERIC ANTIGEN RECEPTOR-TARGETING LIGANDS AND USES THEREOF

Exclusively Licensed Technology / Case number: #22227H
Darrell J Irvine / Benjamin Cossette / Leyuan Ma / Naveen Mehta / Karl Dane Wittrup
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Neuronal Axon Mimics Enabled by Projection Stereolithography and Hybrid Electrospinning-Printing

Exclusively Licensed Technology / Case number: #19488Q
Krystyn Van Vliet / Huifeng Du / Alexis Lowe / Daniela Espinosa Hoyos / Anna Jagielska / Hyunwoo Yuk / Xuanhe Zhao / Xuanlai Fang
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living

RNA-based Logic Circuits with RNA Binding Proteins, Aptamers and Small Molecules

Exclusively Licensed Technology / Case number: #16631HJ
Darrell J Irvine / Kei Endo / Hirohide Saito / Tyler Wagner / Jacob Becraft / Katie Bodner / Tasuku Kitada / Velia Siciliano / Maria Hottelet Foley / Liliana Wroblewska / Ron Weiss
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Gene Editing by Cystolic Intracellular Delivery

Exclusively Licensed Technology / Case number: #17635J
Robert Langer / Alexandra Eyerman / Prashant Mali / Marc Lajoie / Armon Sharei / Klavs F. Jensen
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Enhancement of Peptide Antigenicity for T Cell Priming Using Albumin Binding Peptides

Exclusively Licensed Technology / Case number: #19388H
Darrell J Irvine / Rebecca Holden / Kelly Moynihan / Bradley L. Pentelute
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Method for Noninvasive Extraction of Fetal Cardiac Signals from Maternal Abdominal Recordings

Exclusively Licensed Technology / Case number: #13469J
Gari Clifford / Mohammed Shamsollahi / Christian Jutten / Reza Sameni
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living

A Network-Based Approach to Analyze and Integrate Untargeted Metabolomics with Various High-Throughput Experimental Data

Exclusively Licensed Technology / Case number: #17394
Ernest Fraenkel / Leila Pirhaji
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Circulating Tumor Cell Isolation by Size Selective Tagging in a Microfluidic Device

Exclusively Licensed Technology / Case number: #16239
Robert Langer / Nahyun Cho / Viktor Adalsteinsson / Armon Sharei / J. Christopher Love / Klavs F. Jensen
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living

Activation Induced Clipping System

Technology / Case number: #24546J
Jianzhu Chen / Alaa Ali / Rizwan Romee / Guozhu Xie
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Microfabricated Biopolymer Scaffolds and Method of Making Same

Exclusively Licensed Technology / Case number: #11946J
Sangeeta Bhatia / Giovanni Vozzi / No Inventor
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

'Inverse Patterning' Process for 3D Multi-Compartmental Micro-Organization of Multiple Cell Types

Exclusively Licensed Technology / Case number: #15455H
Sangeeta Bhatia / Kelly Stevens
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

In Situ Sequencing of Expanded Biological Specimens

Non-Exclusively Licensed Technology / Case number: #17496TEYJQ
Edward Stuart Boyden / Shahar Alon / Evan Daugharthy / Adam Marblestone / Paul Tillberg / Fei Chen / George Church
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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