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Compact, Portable, Re-Configurable Unit for Making On-Demand Pharmaceutical Tablets

Technology / Case number: #19221
Allan S. Myerson / Mohammad Azad / Juan Osorio Caicedo / Gregory Hammersmith / David Brancazio
Technology Areas: Drug Delivery / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Peptide-Targeted Layer-by-Layer Nanoparticle for Glioblastoma Treatment

Technology / Case number: #25659
Natalie Boehnke / Nicholas Lamson / Andrew Pickering / Priya Ganesh / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Conformable Ultrasound Face Patch for Cavitation Enhanced Transdermal

Technology / Case number: #24824TE
Canan Dagdeviren
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Ionizable Lipid OF-02 and its Use in mRNA Delivery

Technology / Case number: #17733
Joseph Dorkin / Owen Fenton / Kevin Kauffman / Rebecca McClellan / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Human Microbiome Clostridia-Derived Biosynthetic Enzymes/Pathways for the Biological Production of Natural and Non-Natural Fatty Acylated Compounds

Technology / Case number: #20961
Christopher Voigt / Fang-Yuan Chang
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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In Vitro and in Vivo Delivery of Complex Genetic Circuits up to 33kb Using Engineered HSV-1

Technology / Case number: #20746
Ron Weiss / Maria Hottelet Foley / Jin Huh / Ross Jones
Technology Areas: Diagnostics / Drug Delivery
Impact Areas: Healthy Living
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Oligomeric Conjugates for siRNA Delivery and Glucose-Responsive Insulins

Technology / Case number: #15977J
Arturo Vegas / Rosemary Kanasty / Robert Langer / Daniel Anderson
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Lipids and Formulations for Intramuscular and Systemic Delivery of mRNA

Technology / Case number: #25351J
Arnab Rudra / Akash Gupta / Kaelan Reed / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Layer-by-Layer Based Nanoparticles for Systemic Delivery Applications

Technology / Case number: #14680
Zhiyong Poon / Paula Hammond
Technology Areas: Chemicals & Materials / Computer Science / Drug Delivery
Impact Areas: Healthy Living
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Tunable Structure of Biodegradable Silk-Based Microcapsules for Soluble and Insoluble Payload Delivery

Technology / Case number: #23764J
Benedetto Marelli / Muchun Liu / Pierre-Eric Millard / Henning Urch / Ophelie Zeyons / Rupert Konradi / Bernd Oschmann / Yagmur Yegin
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Vibrating Ingestible BioElectronic Stimulator (VIBES)

Technology / Case number: #23759JQ
Giovanni Traverso / Shriya Sruthi Srinivasan / Robert Langer / Amro Alshareef
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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A Handheld Closed-Loop Automatic Insulin Delivery System

Technology / Case number: #22018J
Giovanni Traverso / Hen Wei Huang / Sean You / Erin Raftery / Canchen Li
Technology Areas: Biotechnology / Communication Systems / Drug Delivery
Impact Areas: Healthy Living
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Luke Rhym / Allen Jiang / Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Bowen Li / Akiva Gordon / Idris Raji / Daniel Anderson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Cellular Backpacks for Drug Delivery Across the Blood-Brain Barrier

Technology / Case number: #18547J
Roberta Polak / Elena Batrakova / Matthew Haney / Yuling Zhao / Natalya Klyachko / Michael F Rubner / Robert Cohen
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Oleogel Drug Delivery Systems for Pediatric Applications

Technology / Case number: #22116J
Giovanni Traverso / Ameya Kirtane / Robert Langer / Aniket Wahane / Christina Karavasili
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Machine Learning for the Design of Cancer Vaccine Adjuvants

Technology / Case number: #21680J
Giovanni Traverso / Ameya Kirtane / Daniel Reker / Robert Langer / Lewis Scott Jones / Hyunjoon Kim / Netra Kamat
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Crystalline and Amorphous Formulations Used to Deliver Anti-Fibrotic (and other) Compounds in Conjunction with Implanted Materials (Cells/Devices)

Technology / Case number: #18287J
Joshua Doloff / Shady Farah / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
License

Anti-Zika Virus Antibodies

Technology / Case number: #18525J
Kannan Tharakaraman / Eng Ooi / Kuan Chan / Satoru Watanabe / Subhash Vasudevan / Ram Sasisekharan
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Ionizable Lipids for Messenger RNA Delivery

Technology, Tangible Property / Case number: #24861
Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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