Lipid Nanoparticles for Drug Delivery to Microglia in the Brain
Invention type: Technology
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Case number: #23156P
The present disclosure provides methods of inhibiting amyloid synthesis in a subject using small molecule inhibitors. The invention also includes methods of treating disease associated with amyloid synthesis, such as Alzheimer's disease. The small molecule inhibitors disclosed herein are compounds which are non-immunosuppressant cyclosporin including the pharmaceutically acceptable salts thereof.
Researchers
Robert Langer
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William Ralvenius
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Julia Bonner
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Jason Andresen
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Joel Blanchard
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Owen Fenton
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Li-Huei Tsai
Departments: Office of the Institute Professors, DLC Heads Science
Technology Areas: Chemicals & Materials: Nanotechnology & Nanomaterials / Drug Delivery: Microparticles & Nanoparticles / Therapeutics: Nucleic Acids
Impact Areas: Healthy Living
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lipid nanoparticles for drug delivery to microglia in the brain
United States of America | Published application
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