Linking Immune Receptor Sequence to Single Cell Transcriptome at Scale

The invention includes methods for enriching for T cell receptor- or B cell receptor-encoding transcripts from a single cell RNA sequencing library, (ii) sequencing T cell receptor- or B cell receptor-encoding transcripts from a single cell RNA sequencing library, and (iii) targeted tagmentation of T cell receptor- or B cell receptor-encoding transcripts. 

Researchers

John Love / Todd Gierahn / Ang Tu

Departments: Department of Chemical Engineering
Technology Areas: Drug Discovery and Research Tools: Genomics & Proteomics
Impact Areas: Healthy Living

  • methods for analyzing t cell receptors and b cell receptors
    United States of America | Published application

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