Highly Parallel Profiling of Enzymes In Vivo Using Mass-Encoded Substrate Libraries
Invention type: Technology
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Case number: #13062
The present invention relates to methods and products associated with in vivo enzyme profiling. In particular, the invention relates to methods of in vivo processing of exogenous molecules followed by detection of signature molecules as representative of the presence of active enzymes associated with diseases or conditions. The invention also relates to products, kits, and databases for use in the methods of the invention.
Researchers
Geoffrey Von Maltzahn
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Gabriel Kwong
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Sangeeta Bhatia
Departments: Health Sciences and Technology Program
Technology Areas: Biotechnology: Sensors & Monitoring / Diagnostics: Assays / Therapeutics: Proteins & Antibodies
Impact Areas: Healthy Living
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methods and products for in vivo enzyme profiling
United States of America | Granted | 8,673,267 -
highly parallel profiling of enzymes in vivo using mass-encoded substrate libraries
Canada | Granted | 2,754,072 -
methods and products for in vivo enzyme profiling
European Patent Convention | Granted | 2,403,964 -
methods and products for in vivo enzyme profiling
Japan | Granted | 6,067,225 -
methods and products for in vivo enzyme profiling
United States of America | Granted | 9,970,941 -
methods and products for in vivo enzyme profiling
United States of America | Granted | 10,883,998 -
methods and products for in vivo enzyme profiling
Canada | Granted | 3,026,701 -
methods and products for in vivo enzyme profiling
United States of America | Granted | 11,703,510 -
methods and products for in vivo enzyme profiling
European Patent Convention | Published application -
methods and products for in vivo enzyme profiling
Switzerland | Granted | 2,403,964 -
methods and products for in vivo enzyme profiling
Liechtenstein | Granted | 2,403,964 -
methods and products for in vivo enzyme profiling
Germany | Granted | 2,403,964 -
methods and products for in vivo enzyme profiling
Spain | Granted | 2,403,964 -
methods and products for in vivo enzyme profiling
France | Granted | 2,403,964 -
methods and products for in vivo enzyme profiling
Italy | Granted | 2,403,964 -
methods and products for in vivo enzyme profiling
United Kingdom | Granted | 2,403,964 -
methods and products for in vivo enzyme profiling
United States of America | Granted | 11,549,951 -
methods and products for in vivo enzyme profiling
United States of America | Published application
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