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Optimized Opsin Trafficking with Fluorescence-Dead Protein Fusions

Technology / Case number: #18783TE
Edward Boyden / Kiryl Piatkevich / Aimei Yang / Demian Park
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Tri-Functional Hydrophilic Self-Crosslinked Dimethylacrylamide Polymer

Technology / Case number: #18698TEM
Edward Boyden / Linyi Gao / Ruixuan Gao / Nikita Obidin
Technology Areas: Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Device and Method for Imaging Shortwave Infrared Autofluorescence

Technology / Case number: #18527J
Oliver Bruns / Jessica Carr / Klaus Van Leyen / Yi Zheng / Marianne Aellen / Moungi Bawendi
Technology Areas: Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Cellular Backpacks for Drug Delivery Across the Blood-Brain Barrier

Technology / Case number: #18547J
Roberta Polak / Elena Batrakova / Matthew Haney / Yuling Zhao / Natalya Klyachko / Michael Rubner / Robert Cohen
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Anti-Zika Virus Antibodies

Technology / Case number: #18525J
Kannan Tharakaraman / Eng Ooi / Kuan Chan / Satoru Watanabe / Subhash Vasudevan / Ram Sasisekharan
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Pooled Screening Identifies Genomic Features (Biomarkers) Modulating Nanoparticle-Cell Interactions

Technology / Case number: #22785J
Angela Koehler / Natalie Boehnke / Joelle Straehla / Paula Hammond
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Spatially Localized Gene Delivery of Adeno-Associated Viruses

Technology / Case number: #25055
Polina Anikeeva / Keisuke Nagao
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Ultrastructural Membrane Expansion Microscopy

Technology / Case number: #25088HM
Edward Boyden / Tay Won Shin
Technology Areas: Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Near and Shortwave Infrared Polymethine Dyes

Technology / Case number: #19474
Ellen Sletten / Justin Caram / Timothy Swager
Technology Areas: Diagnostics / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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Method for Point-of-use Testing for Bacteriological Water Contamination in Resource-Limited Environments

Technology / Case number: #19080
Rohit Karnik / Emily Hanhauser / Michael Bono / Chintan Vaishnav / Sydney Beasley / Anastasios Hart
Technology Areas: Biotechnology / Diagnostics / Environmental Engineering / Sensing & Imaging
Impact Areas: Healthy Living
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Scalable and Safe Quantum Dot Precursor

Technology / Case number: #20834
Daniel Franke / Matthias Ginterseder / Moungi Bawendi
Technology Areas: Chemicals & Materials / Diagnostics / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Device and Method for Isolation and Detection of Target Cells/Particles from Complex Background Matrices

Technology / Case number: #20847
Rohit Karnik / Emily Hanhauser / Michael Bono / Mary Strawser
Technology Areas: Diagnostics
Impact Areas: Healthy Living
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Near Infrared Fluorescent Biosensors for Steroid Hormones

Technology / Case number: #21434
Michael Strano / Michael Lee / Naveed Bakh / Song Wang
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Quantitative Ultra-sensitive Detection of Biological Species

Technology / Case number: #21467
Suchol Savagatrup / Kosuke Yoshinaga / Jie Li / Zachary Nelson / Cassandra Zentner / Timothy Swager
Technology Areas: Agriculture & Food / Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Extending Fluorescent Assays In Vivo for Biomedical Sensing: Wavelength Modulation Spectroscopy

Technology / Case number: #22003
Michael Strano / Volodymyr Koman / Naveed Bakh
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Device and Method for Isolation and Detection of Soluble or Particulate Analytes from Complex Background Matrices

Technology / Case number: #23246
Rohit Karnik / Krithika Ramchander / Emily Hanhauser / Mary Strawser / Chun Man Chow
Technology Areas: Agriculture & Food / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living, Sustainable Future
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Antibody-Free Rapid Detection of SARS-CoV-2 Proteins Using Corona Phase Molecular Recognition (CoPhMoRe)

Technology / Case number: #23605
Michael Strano / Xun Gong / Sooyeon Cho / Xiaojia Jin / Sungyun Yang / Jianqiao Cui
Technology Areas: Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Label-Free Detection of Oligonucleotide Hybridization Using Anchored Single-Walled Carbon Nanotube Corona Phase

Technology / Case number: #24626
Michael Strano / Xun Gong / Sooyeon Cho / Xiaojia Jin / Sungyun Yang / Jianqiao Cui
Technology Areas: Chemicals & Materials / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Using Cross-Dressing to Enhance Anti-Tumor Immune Responses

Technology / Case number: #21679
Stefani Spranger / Ellen Duong
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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1. Methods for in Vitro Evolution of Constructs Derived from Viruses. 2. Five Mutations Derived from the in Vitro Evolution. 3. Seventeen constructs from the five mutations.

Technology / Case number: #20395H
Ron Weiss / Yingzhong Li / Darrell Irvine
Technology Areas: Biotechnology / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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