Optimized Opsin Trafficking with Fluorescence-Dead Protein Fusions
Invention type: Technology
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Case number: #18783TE
The invention, in some aspects, relates to dummy-fluorescent (DF) polypeptide molecules and their encoding nucleic acid molecules and use of such molecules in fusion proteins and their encoding nucleic acid molecules. Compositions of the invention may be delivered to cells and subjects and used in methods to modulate electrical activity of cells in which they are expressed, and for treatment of diseases and conditions in subjects.
Researchers
Departments: Department of Brain and Cognitive Sciences, McGovern Institute for Brain Research
Technology Areas: Biotechnology: Synthetic Biology / Diagnostics: Imaging Agents / Drug Discovery and Research Tools: Genomics & Proteomics / Therapeutics: Cell Based Therapy, Nucleic Acids, Proteins & Antibodies
Impact Areas: Healthy Living
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dummy-fluorescent protein fusions and methods of use
United States of America | Granted | 11,278,633
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