Device and Method for Imaging Shortwave Infrared Autofluorescence

Systems and methods for measuring short wave infrared fluorescence and autofluorescent signals are disclosed. In some embodiments, for example, a method may include exposing a portion of tissue that does not include a fluorescent probe to an excitation source of the tissue, wherein at least a portion of the tissue has an autofluorescence spectrum which includes wavelengths greater than 900 nm, and imaging the tissue with a detector that is sensitive to electromagnetic radiation with wavelengths greater than or equal to 900 nm. In certain other embodiments, a system comprises a fluorescent probe including a fluorescent component attached to a carrier, an excitation source, and a detector that detects a tail portion of the fluorescence of the fluorescent component. Methods associated with such a system are also disclosed.

Researchers

Oliver Bruns / Jessica Carr / Klaus Van Leyen / Yi Zheng / Marianne Aellen / Moungi G Bawendi

Departments: Department of Chemistry
Technology Areas: Diagnostics: Imaging Agents / Sensing & Imaging: Imaging
Impact Areas: Healthy Living

  • device and method for imaging shortwave infrared fluorescence
    United States of America | Granted | 11,579,088
  • device and method for imaging shortwave infrared fluorescence
    Japan | Published application
  • device and method for imaging shortwave infrared fluorescence
    Japan | Published application

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