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Peptide-Encoded Libraries of Small Molecules for De Novo Drug Discovery

Technology / Case number: #23712
Stephen Buchwald / Simon Roessler / Nathalie Grob / Bradley L. Pentelute
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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DNA-Dye Assembly Based Single-Molecule Fluorescence Lifetime Imaging Probes

Technology / Case number: #23780
Mark Bathe / Jiajia Guo / Gabriela Schlau-Cohen / Xiao Wang / Stephanie Hart
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Fabrication of Polymeric Microneedles with Hollow and Porous Tips via a Simple Micromolding Process Assisted by Ionic Salts

Technology / Case number: #24093
Benedetto Marelli / Doyoon Kim
Technology Areas: Agriculture & Food / Chemicals & Materials
Impact Areas: Advanced Materials
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Tissue-integrating Neural Interfaces

Technology / Case number: #24351
Polina Anikeeva / Anthony Tabet
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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An Ingestible Stackable Gastric Resident System for Gastrointestinal Applications

Technology / Case number: #25424J
Robert Langer / Matt Murphy / SeungHo Lee / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Communication Systems
Impact Areas: Healthy Living
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Core-shell Nanodisc Synthesis and Applications to Single-Particle Targeted Magnetothermal Control of Biological Signaling

Technology / Case number: #24461
Polina Anikeeva / Florian Koehler / Ye Ji Kim
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Double Core-shell Nanodisc Synthesis and Application to Magnetoelectric Bio-signaling

Technology / Case number: #24486
Polina Anikeeva / Florian Koehler / Ye Ji Kim
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Cleavable Additives Enable On-Demand Degradable Non-Aromatic Polyurethanes

Technology / Case number: #24572
Jeremiah A. Johnson / Yasmeen Alfaraj / Alayna Johnson / Valerie Lensch / Keith Husted
Technology Areas: Chemicals & Materials
Impact Areas: Sustainable Future, Advanced Materials
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Novel Silyl Carbamate Synthesis and Poly(silyl Carbamates) (PSiUs) by Reaction of Silanols with Isocyanates

Technology / Case number: #24596
Jeremiah A. Johnson / Valerie Lensch / Keith Husted
Technology Areas: Chemicals & Materials
Impact Areas: Sustainable Future, Advanced Materials
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Non-Fibrotic Implantable Devices on Diverse Organs

Technology / Case number: #24648
Xuanhe Zhao / Jue Deng / Jingjing Wu / Hyunwoo Yuk
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Cleavable Comonomer Strategy for Accelerating Removal of Gel Nail Polish

Technology / Case number: #24652
Jeremiah A. Johnson / Alexandra Johnson / Leticia Cardoso da Costa / Elisabeth Prince
Technology Areas: Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Ultrafast Single-Step High-Density Conjugation of Quantum Dots and Rods with 2D Lattice Templated Array Alignment using DNA Origami

Technology / Case number: #24671
Mark Bathe / Xin Luo / Chi Chen / Rob Macfarlane
Technology Areas: Chemicals & Materials / Electronics & Photonics
Impact Areas: Advanced Materials
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M13 Bacteriophage with a High Cysteine Content and Genetically Engineerable Hydrogels

Technology / Case number: #22369
Angela Belcher / Nimrod Heldman / William Records
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Dynamic Control of a Fiber Manufacturing Process using Deep Reinforcement Learning

Technology / Case number: #22652
Brian Anthony / Sangwoon Kim / Donghyun Kim
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Industrial Engineering & Automation
Impact Areas: Connected World
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Crosslinking Comonomers for High Performance Degradable Thermosets

Technology / Case number: #22863
Jeremiah A. Johnson / Keith Husted / Peyton Shieh
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Reconfigurable Multistep Chemical Synthesis System

Technology / Case number: #18563
Klavs F. Jensen / Aaron Bedermann / Kosi Aroh / Dale Thomas / Andrea Adamo / Timothy F Jamison
Technology Areas: Chemicals & Materials
Impact Areas: Sustainable Future
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Catalyst Composition and Methods Comprising Metal-Organic Frameworks and Uses thereof in olefin Polymerization

Technology / Case number: #18344
Mircea Dinca / Robert Comito
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Compositions and Methods for Forming Emulsions

Technology / Case number: #18318
Daniel Blankschtein / Vishnu Sresht / Julia Kalow / Lauren Zarzar / Ellen Sletten / Timothy Manning Swager
Technology Areas: Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Redox-Functionalized Electrodes for Selective Electrochemical Separation, Molecular Recognition and Energy Storage as Well as Other Related Applications

Technology / Case number: #18239
T. Alan Hatton / Demetra Achilleos / Xiao Su
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Complex Liquid Crystal Droplets

Technology / Case number: #21760
Timothy Manning Swager / Alberto Concellon Allueva / Cassandra Zentner
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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