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Plk1 inhibitor and Microtubule Poison Dual Payload Antibody Drug Conjugates for the Treatment of Cancer

Technology / Case number: #26136
Michael Yaffe / Jesse C Patterson
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Lipid-Polymer Microparticles (mLPM) For Thermostable, Pulsatile mRNA-LNP Vaccines

Technology / Case number: #26154
Robert Langer / Yuting Huang / Linzixuan Rhoda Zhang / Ana Jaklenec
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Polymeric Core-Shell Particles for Pulsatile Release of HIV Vaccine

Technology / Case number: #26230
Robert Langer / Stacey Lin / Aki Gurram / Rishi Das / Amy Lee / Behnaz Eshaghi / Maria Kanelli / Ana Jaklenec
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Branched Poly(-amino esters) for the Delivery of Nucleic Acids

Technology / Case number: #20333JQ
Robert Langer / Gary Liu / James Byrne / Netra Kamat / Hyunjoon Kim / Daniel Reker / Grace Junyue Zhong / Ameya Kirtane / Yunhua Shi / Giovanni Traverso
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Amino Acid, Peptide, Polypeptide-Lipids (APPL) Derivatives and Uses Thereof

Technology / Case number: #14910Q
Robert Langer / Akinleye Alabi / Yunlong Zhang / Yizhou Dong / Yi Chen / Delai Chen / Arturo Vegas / Kevin Love / Daniel Anderson
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Methods for Microbial Oil Overproduction from Cellulosic Materials

Technology / Case number: #15695
Gregory Stephanopoulos / Mitchell Tai
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Healthy Living, Sustainable Future
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Hardware Synthesis from Multicycle Rules

Technology / Case number: #13362
Technology Areas: Chemicals & Materials / Computer Science / Industrial Engineering & Automation
Impact Areas: Connected World
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Colloidal Hydrogel Particles with tunable Chemistry, Geometry, and Flexibility

Technology / Case number: #13461J
Mehmet Toner / Patrick Doyle
Technology Areas: Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
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Alkyne-Assisted Growth of Carbon Nanotubes by Catalytic Chemical Vapor Deposition

Technology / Case number: #13779J
Anastasios John Hart / Desiree Plata
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Connected World, Advanced Materials
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Method for Quantitative Monitoring of In Vivo Tumor Oxygenation

Technology / Case number: #19207JQ
Michael Cima / Ehud Schmidt / Robert Cormack / Larissa Lee / Gregory Ekchian
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Strategy for Installing Hydrophobic Chains Plus Phosphorus Ligands onto MOFs

Technology / Case number: #25160
Mircea Dinca / Nathan Gin / Valiallah Hosseininasab
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Reprogram the Genome of M13 Phage for Vaccination and Immunotherapy Applications

Technology / Case number: #25169
Angela Belcher / Shengnan Huang
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Multistage Absorption and Desorption for Electrochemically Mediated CO2 Separations

Technology / Case number: #26011
T. Alan Hatton / Michael Edward Lev Massen-Hane / Michael Nitzsche
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Connected World
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A Mechanical Underwater Soft Adhesion System for Kinetic Biosensing and Intelligent Targeted Drug Delivery

Technology / Case number: #26028J
Giovanni Traverso / Yubin Cai / Troy Ziliang Kang / Ming Zhao / Ameya Kirtane
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Expression Constructs for One-Step Construction of Allogeneic CAR-NK Cells

Technology, Tangible Property / Case number: #26118J
Jianzhu Chen / Fuguo Liu / Rizwan Romee
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Connected World
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Using a Genetically Modified Human IPS Line to Screen for Drugs that Prevent or Treat Alzheimer's Disease

Technology / Case number: #26292P
Li-Huei Tsai / Masayuki Nakano / Matheus Victor / Leyla Akay / TaeHyun Kim
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Automated Spray-LbL Technology

Technology / Case number: #12307
Paula Hammond
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Sustainable Future, Connected World
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High Power Materials Development of Olivine System Using Non-Stoichiometry or Surface Coating Method

Technology / Case number: #12347
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Sustainable Future
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Amplitude Spectroscopy of a Solid-State Artificial Atom

Technology / Case number: #13407L
Karl Berggren / William Oliver
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Lock Release Lithography

Technology / Case number: #13438
Patrick Doyle
Technology Areas: Chemicals & Materials
Impact Areas: Connected World
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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