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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods for Improving Cross-Ancestry Transferability in Predicting Polygenic Phenotypes from Genetic Variation

Technology / Case number: #24858
Manolis Kellis / Yosuke Tanigawa
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Inorganic Glass Composite Solid Electrolytes for Lithium or Sodium Batteries

Technology / Case number: #25304
Ju Li / Tao Dai
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Sustainable Future
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Bioelectronic Devices to Support Transplanted Cells in Vivo for Encapsulated Cell Therapies

Technology / Case number: #23269J
Suman Bose / Robert Langer / Siddharth Krishnan / Matthew Bochenek / Nima Khatib / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living
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Multisensory Gamma Stimulation Promotes Glymphatic Clearance of Amyloid

Technology / Case number: #25696PH
Li-Huei Tsai / Edward Boyden / Ping-Chieh Pao / Cheng-Yi Yang / Mitchell Murdock
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Composite Anti-Fouling Coatings Designed via Full Spectral Hamaker Constant Minimization

Technology / Case number: #21606J
Michael Short / Max Carlson / Robert Simpson
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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Chemical Compositions for Porous Lithium Anodes Enabling Coble Creep Mechanism in Solid State Electrolyte-Based Batteries with No Applied Stack Pressure

Technology / Case number: #23699J
Ju Li / Andrea Maurano / Yuming Chen / Ziqiang Wang / So Yeon Kim / Kai Pei
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Sustainable Future, Connected World
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Adaptive, Integrated Mycotecture for Food, Composites and Mycoremediation

Technology / Case number: #24500X
Andreas Mershin
Technology Areas: Agriculture & Food / Chemicals & Materials
Impact Areas: Climate Stabilization
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Software to Compute the Elastic Response of Thin Plates and Shells (Monolayers and Bilayers) to Growth

Software / Case number: #20823
Willem van Rees
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Sustainable Future
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Vector Representations of Protein Sequences Learned from Structure (Software)

Software / Case number: #20851
Tristan Bepler
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Connected World
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A Software Platform for Transcriptomic Analysis

Software / Case number: #21368
Paul Boutz / Arjun Bhutkar / Arundeep Singh
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Connected World
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A General Stress Patterning Method for Manufacturing Ultra-Precise Free-Form Deformation in Thin-Substrates

Technology / Case number: #21717
Youwei Yao / Brandon Chalifoux / Mark Schattenburg
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Optical Devices based on Phase Change Materials

Technology / Case number: #22247
Juejun Hu / Tian Gu / Yifei Zhang / Carlos Andres Rios Ocampo / Mikhail Shalaginov / Xiaoming Qiu
Technology Areas: Chemicals & Materials / Sensing & Imaging
Impact Areas: Advanced Materials
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Additively Manufactured Metal Matrix Composites

Technology / Case number: #24922
Ju Li / Alexander O'Brien / Emre Tekoglu
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Sustainable Future, Connected World
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Machine Learning Models for Data-Driven Bioprocess Development

Software / Case number: #23675
Connor Coley / Aparajita Dasgupta
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Discovery and Research Tools / Industrial Engineering & Automation
Impact Areas: Healthy Living, Connected World
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Alloy Design Software Platform

Software / Case number: #24721
Gregory Olson / Seyedeh Mohadeseh Taheri Mousavi / Anastasios Hart
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Using CRISPR/Cas9 to Encode Cellular History

Technology / Case number: #18025R
Alexander Shalek / Alethe Gaillard de Saint Germain
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Genotype-Directed Local Delivery of Targeted Therapeutics at the Tumor Margin

Technology / Case number: #19863J
Carlo Giovanni Traverso / Ameya Kirtane / Daniel Cahill / Ganesh Shankar / Robert Langer
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Formulated, Biodegradable Polymeric Nanoparticles for Nucleic Acid Delivery to Non-Liver Targets

Technology / Case number: #19802
Kevin Kauffman / James Kaczmarek / Asha Patel / Luke Rhym / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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High-Throughput Screens for Exploring Biological Functions of Microscale Biological Systems

Technology / Case number: #19737JR
Paul Blainey / Navpreet Ranu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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