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Structure-Guided Chemical Modification of Guide RNA and its Applications

Technology / Case number: #19175V
Hao Yin / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Derivation of Enteroendocrine Cells and Insulin Expressing Cells

Technology / Case number: #18445J
Jeffrey Michael Karp / Xiaolei Yin / Robert Langer
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Photosensitized-Photoactive Materials and Methods for Making and Using the Same

Technology / Case number: #17987J
Mohammad Gondal / Gibum Kwon / Gareth McKinley / Kripa K Varanasi
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Crystalline and Amorphous Formulations Used to Deliver Anti-Fibrotic (and other) Compounds in Conjunction with Implanted Materials (Cells/Devices)

Technology / Case number: #18287J
Joshua Doloff / Shady Farah / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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sgRNA Chemical Modification for Efficient Gene Editing

Technology / Case number: #17805V
Hao Yin / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Fully Implantable, Autonomous Closed-Loop System Capable of Long-Term Vital Signs Monitoring and Performing Lifesaving Treatment

Technology / Case number: #23387J
Giovanni Traverso / Hen Wei Huang / SeungHo Lee / Saurav Maji / Peter Chai / Tom Kerssemakers / Ian Ballinger / Anantha Chandrakasan
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
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User-Friendly and Easily-Accessible Synthetic Hydrogels for Biomaterials Application

Technology / Case number: #20694
Owen Fenton / Robert Langer / Jason Andresen / Marion Paolini
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Pore Creation Methods in Monolayer Graphene for Membrane Applications

Technology / Case number: #18915J
Jing Kong / Rohit N Karnik / Tahar Laoui / Piran Kidambi / Ahmed Ibrahim / Sui Zhang
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Advanced Materials
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DNA Based Immobilization for Improved Electrochemical Carbon Dioxide Reduction

Technology / Case number: #23961
Ariel Furst / Gang Fan
Technology Areas: Biotechnology / Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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Thin-film Nanocomposite Membranes for Separating Ions and Uncharged Species in Water

Technology / Case number: #24335
Zachary P Smith / Gang Han
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Additive Manufacturing of Composite Powders

Technology / Case number: #22913L
Ethan Parsons
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
Labels
  • Additive Manufacturing
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Magnetically Responsive Inks for 3D Printing

Technology / Case number: #21387LJ
Jennifer Lewis / Brad Duncan / Theodore Fedynyshyn
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
Labels
  • Additive Manufacturing
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Ionizable Lipids for Messenger RNA Delivery

Technology, Tangible Property / Case number: #24861
Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Thermo-Responsive, Inflammation-Targeting (TRIT) Hydrogel Formulations for Local Drug Delivery in Intestinal Inflammation

Technology / Case number: #19181J
Giovanni Traverso / Sufeng Zhang / Ashok Kakkar / Joshua Korzenik / Robert Langer
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Tough Hydrogel Pills Inflating 100 Times in Volume Within 10 Min

Technology / Case number: #20059
Xuanhe Zhao / Shaoting Lin / Hyunwoo Yuk / German Parada Hernandez / Xinyue Liu
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Gastric Residence Electronics

Technology / Case number: #20092J
Giovanni Traverso / Yong Lin Kong / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Communication Systems
Impact Areas: Healthy Living
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Transparent Luminescent Displays Enabled by Electric-Field-Induced Quenching of Photoluminescent Pixels

Technology / Case number: #17634
Jeffrey C. Grossman / Geoffrey Supran / Patrick Brown / Moungi G Bawendi / Vladimir Bulovic
Technology Areas: Chemicals & Materials / Electronics & Photonics
Impact Areas: Advanced Materials
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Microelectromechanical Systems for Acoustics

Technology / Case number: #19512
Apoorva Murarka / Vladimir Bulovic / Jeffrey Lang
Technology Areas: Biotechnology / Chemicals & Materials / Electronics & Photonics
Impact Areas: Healthy Living, Advanced Materials
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Upconversion Utilizing Thin Film Colloidal Nanocrystals and Organic Materials

Technology / Case number: #17808
Daniel Congreve / Nicholas Thompson / Mark Wilson / Mengfei Wu / Moungi G Bawendi / Vladimir Bulovic / Marc Baldo
Technology Areas: Biotechnology / Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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Hybrid Materials with Living Cells and Tough Hydrogels

Technology / Case number: #18548
Timothy K Lu / Xuanhe Zhao / Eleonore Tham / Xinyue Liu / Tzu-Chieh Tang
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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