Nanoscale Imaging of Proteins and Nucleic Acids via Expansion Microscopy
Non-Exclusively Licensed
Invention type: Technology
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Case number: #18127TEYJQ
The invention enables in situ genomic and transcriptomic assessment of nucleic acids to be conducted in biological specimens that have been physically expanded. The invention leverages the techniques for expansion microscopy (ExM) to provide new methods for in situ genomic and transcriptomic assessment of nucleic in a new process referred to herein as “expansion fluorescent in situ hybridization” (ExFISH).
Researchers
Edward Stuart Boyden
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Shahar Alon
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Evan Daugharthy
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Fei Chen
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Asmamaw Wassie
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George Church
Departments: Department of Brain and Cognitive Sciences, Health Sciences and Technology Program
Technology Areas: Biotechnology: Sensors & Monitoring / Diagnostics: Imaging Agents / Sensing & Imaging: Imaging, Optical Sensing
Impact Areas: Healthy Living
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nanoscale imaging proteins and nucleic acids via expansion microscopy
Ireland | Granted | 3,332,029 -
nanoscale imaging of proteins and nucleic acids via expansion microscopy
United States of America | Granted | 10,364,457 -
nanoscale imaging of proteins and nucleic acids via expansion microscopy
Canada | Granted | 2,994,958 -
nanoscale imaging proteins and nucleic acids via expansion microscopy
European Patent Convention | Granted | 3,332,029 -
nanoscale imaging of proteins and nucleic acids via expansion microscopy
China | Granted | 0 -
nanoscale imaging proteins and nucleic acids via expansion microscopy
Belgium | Granted | 3,332,029 -
nanoscale imaging proteins and nucleic acids via expansion microscopy
Switzerland | Granted | 3,332,029 -
nanoscale imaging proteins and nucleic acids via expansion microscopy
Liechtenstein | Granted | 3,332,029 -
nanoscale imaging proteins and nucleic acids via expansion microscopy
Germany | Granted | 3,332,029 -
nanoscale imaging proteins and nucleic acids via expansion microscopy
France | Granted | 3,332,029 -
nanoscale imaging proteins and nucleic acids via expansion microscopy
United Kingdom | Granted | 3,332,029
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