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Multicellular Integrated Brain Tissue for Investigation and Therapeutic Discovery in Neurological Diseases

Technology / Case number: #22618P
Robert Langer / Adele Bubnys / Alice Stanton / Joel Blanchard / Li-Huei Tsai
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Perfusable Host Microfluidic Endothelial Networks for Spheroid and Organoid Co-culture and Immune Cell Infiltration Studies

Technology / Case number: #22749
Roger Kamm / Sharon Lee / Huu Tuan Nguyen
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Fusion Capsid Therapy for COVID-19 and Applies to Other Viruses: Universal "Dominant" Antiviral to Prevent Virus Evolution and Future Pandemics (DNA/RNA/Protein)

Technology, Tangible Property / Case number: #22801MH
Robert Langer / Bowen Li / Yong Qian / Alexi Choueiri / Edward Stuart Boyden / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Crosslinking Comonomers for High Performance Degradable Thermosets

Technology / Case number: #22863
Jeremiah A. Johnson / Keith Husted / Peyton Shieh
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Novel Peptides to Inhibit Ena/VASP Proteins

Technology / Case number: #22897J
Amy Keating / Samantha Hill / Ghassan Mouneimne / Sara Parker / Meucci IIunga / Theresa Hwang
Technology Areas: Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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A Tunable Phosphorylation-based Feedback Controller of Mammalian Gene Expression

Technology / Case number: #22932
Ron Weiss / Yili Qian / Domitilla Del Vecchio / Ross Jones
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Fluidic Platform for Perfusable Vascularized Tumor Spheroids and Organoids

Technology / Case number: #22942
Roger Kamm / Shun Zhang / Zhengpeng (Jason) Wan
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Lectin Fingerprinting for Mapping Viral Glycosylation and Identifying Neutralizing Antibodies

Technology / Case number: #22955
Laura L Kiessling / Amanda Dugan / Michael Wuo
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Molecular Imaging with LisNRs, A Novel Class of Liposome-based Contrast Agents Based on Modulation of Membrane Water Permeability

Technology / Case number: #23006
Alan Pradip Jasanoff / Jacob Simon
Technology Areas: Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Identification of Genes and Mutations that Underlie Adaptation of Gut Microbes to Denovo Degradation of Oxalate

Technology / Case number: #23007
Jeff Gore / Avihu Yona
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Reconfigurable Multistep Chemical Synthesis System

Technology / Case number: #18563
Klavs F. Jensen / Aaron Bedermann / Kosi Aroh / Dale Thomas / Andrea Adamo / Timothy F Jamison
Technology Areas: Chemicals & Materials
Impact Areas: Sustainable Future
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Redox-Electrodes for Electrochemically-Controlled Bio-Macromolecule Interaction: Bio-Separations, Heterogeneous Enzyme Immobilization, Protein Purification and Sensing, Among Others

Technology / Case number: #18540
T. Alan Hatton / Xiao Su
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Robust Anti-Icing Polymer Coatings

Technology / Case number: #18517
Robert Cohen / Dayong Chen / Gareth McKinley
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Nanostructure Growth at Low Temperatures via Na-comprised Compounds

Technology / Case number: #18481
Brian L Wardle / Erica Freire Antunes / Andrew Liotta / Richard Li
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Method to Control and Create Multi-Domain Function and Intelligence in 3D

Technology / Case number: #18452
Wojciech Matusik / Subramanian Sundaram
Technology Areas: Chemicals & Materials / Electronics & Photonics / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Polymer Based Solid-State Solar Thermal Fuels

Technology / Case number: #18399
Jeffrey C. Grossman / David Zhitomirsky
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Catalyst Composition and Methods Comprising Metal-Organic Frameworks and Uses thereof in olefin Polymerization

Technology / Case number: #18344
Mircea Dinca / Robert Comito
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
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Protein-Surfactant-Monomer/Polymer Blends for Protein-Based Elastomers

Technology / Case number: #19861
Bradley D. Olsen / Wui Yarn Chan
Technology Areas: Biotechnology / Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Precision and Digital Flexo-Printing Using Electrostatic Nanoporous Stamp

Technology / Case number: #18320
Anastasios John Hart / Sanha Kim
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Compositions and Methods for Forming Emulsions

Technology / Case number: #18318
Daniel Blankschtein / Vishnu Sresht / Julia Kalow / Lauren Zarzar / Ellen Sletten / Timothy Manning Swager
Technology Areas: Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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