Self-Righting Systems and Related Components and Methods

Self-righting articles, such as self-righting capsules for administration to a subject, are generally provided. In some embodiments, the self-righting article may be configured such that the article may orient itself relative to a surface (e.g., a surface of a tissue of a subject). The self-righting articles described herein may comprise one or more tissue engaging surfaces configured to engage (e.g., interface with, inject into, anchor) with a surface (e.g., a surface of a tissue of a subject). In some embodiments, the self-righting article may have a particular shape and/or distribution of density (or mass) which, for example, enables the self-righting behavior of the article. In some embodiments, the self-righting article may comprise a tissue interfacing component and/or a pharmaceutical agent (e.g., for delivery of the active pharmaceutical agent to a location internal of the subject). In some cases, upon contact of the tissue with the tissue engaging surface of the article, the self-righting article may be configured to release one or more tissue interfacing components. In some cases, the tissue interfacing component is associated with a self-actuating component. For example, the self- righting article may comprise a self-actuating component configured, upon exposure to a fluid, to release the tissue interfacing component from the self-righting article. In some cases, the tissue interfacing component may comprise and/or be associated with the pharmaceutical agent (e.g., for delivery to a location internal to a subject).

Researchers

Robert Langer / Brian Jensen / Mette Poulsen / Mikkel Oliver Jespersen / Peter Herskind / Bo Kristiansen / Morten Frederiksen / Jorrit Water / Ester Caffarel Salvador / Niclas Roxhed / Minsoo Khang / Alex Abramson / Taylor Bensel / Giovanni Traverso

Departments: Office of the Institute Professors, Department of Mechanical Engineering
Technology Areas: Industrial Engineering & Automation: Autonomous Systems, Manufacturing & Equipment / Sensing & Imaging: Imaging
Impact Areas: Connected World

  • self-righting systems and related components and methods
    Australia | Granted | 2,018,269,711
  • self-righting systems and related components and methods
    China | Published application
  • self-righting systems and related components and methods
    Israel | Granted | 301,683
  • self-righting systems and related components and methods
    Japan | Granted | 7,550,201
  • self-righting systems and related components and methods
    United States of America | Granted | 12,036,324
  • self-righting systems and related components and methods
    United States of America | Granted | 11,369,574
  • self-righting systems and related components and methods
    Korea (south) | Granted | 10
  • self-righting systems and related components and methods
    Japan | Granted | 7,219,723
  • self-righting systems and related components and methods
    India | Granted | 417,580
  • self-righting systems and related components and methods
    Israel | Granted | 270,450
  • self-righting systems and related components and methods
    European Patent Convention | Published application
  • self-righting systems and related components and methods
    China | Granted | 0
  • self-righting systems and related components and methods
    Canada | Published application

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