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Molecular Time Capsules Enable Transcriptomic Recording in Living Cells

Technology / Case number: #25337
Gene-Wei Li / Mirae Parker / Jack Rubien / Dylan McCormick
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Machine Learning-guided Whole-Organ Optical Imaging Technique for Non-destructive Identification of Early Pre-Cancer Lesions and Harvesting of Viable Cells from the same for Organoid Culture

Technology / Case number: #25480
Neelkanth Manoj Bardhan / Vivek Rastogi / Angela Belcher
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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An Efficient Bioconjugation Technology for Site-Selective Covalent Modification of Antibodies using an Engineered Affinity Peptide

Technology / Case number: #25358
Bradley L. Pentelute / Andrei Loas / Jacob Rodriguez / Heemal Dhanjee / Aurelie Rondon / Katsushi Kitahara
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Medical Recordkeeping Microneedles

Technology / Case number: #24923
Ana Jaklenec / Robert Langer / Maria Kanelli / Jooli Han / Yang Liu / Fredo Durand (he/him/his)
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Non-Invasive Tactile Stimulation for Improving Motor Function

Technology / Case number: #22928P
Li-Huei Tsai / Ho-Jun Suk / Guojie Xu / Arit Banerjee
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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A Tunable Phosphorylation-based Feedback Controller of Mammalian Gene Expression

Technology / Case number: #22932
Ron Weiss / Ross Jones / Domitilla Del Vecchio / Yili Qian
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Single-Cell Density as A Biomarker for Drug Sensitivity

Technology / Case number: #23741J
Keith Ligon / Weida Wu / Teemu Miettinen / Sarah Ishamuddin / Kin-Hoe Chow / Scott Manalis
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Hyperlactatemia Prediction

Technology / Case number: #18128J
Andrew Reisner / Thomas Heldt / Michael Filbin / Max Dunitz / George Verghese
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Computer Science
Impact Areas: Healthy Living
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Overcoming Emission Photon Scattering in Wide-Field Microscopy

Technology / Case number: #20164P
Christopher Rowlands / Jong Kang Park / Yi Xue / Kalen Berry / Balpreet Ahluwalia / Dushan Wadduwage / Peter So / Elly Nedivi
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Advanced Architectures and Operating Principles for Electrochemical Neuro-Modulation

Technology / Case number: #20280J
Daniel Freeman / Matthew Flavin / Jongyoon Han
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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A Multimodal Metric for Tracking Nociception Under Anesthesia

Technology / Case number: #20522J
Emery N Brown / Riccardo Barbieri / Sandya Subramanian
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Leveraging Device-arterial Coupling to Determine Cardiac and Vascular State

Technology / Case number: #20558J
Elazer R Edelman / Brian Chang / Steven Keller / Sonya Sanat Bhavsar / Noam Josephy / Quing Tan / Ahmad El Katerji
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Structures with Complex Geometries and Controlled Porosity in Micrometer to Meter Dimensions Produced at Large Scale

Technology / Case number: #21002J
Polina Anikeeva / Zi Jie Gabriel Loke / Dena Shahriari / Ian Tafel / Yoel Fink
Technology Areas: Biotechnology / Chemicals & Materials
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Arterial Wall Characterization in Optical Coherence Tomography Imaging

Technology / Case number: #21209
Elazer R Edelman / Max Olender / Lambros Anthanasiou
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Emboli Detection Methods to Identify Stroke Mechanism or Stroke Risk in Susceptible Adults and Children

Technology, Software / Case number: #21233J
Thomas Heldt / Syed Imaduddin / Kerri LaRovere / Barry Kussman
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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Fluid Assessment in Dialysis Patients by Point-of-Care Magnetic Relaxometry

Technology / Case number: #21339JQ
Michael Cima / Matthew Li / Lina Colucci / Ashvin Bashyam / Christopher Frangieh / Herbert Lin / Kristin Corapi
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Shape Optimization for Prosthetic Feet

Technology / Case number: #21461
Amos Winter / Victor Prost
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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An Integrated and Automated Electronic System for Point-of-Care Protein Testing

Technology / Case number: #21674
Dan Wu / Joel Voldman
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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An Electrokinetic-based High-Throughput Concentrator for Cells, Bioparticles, and Molecules

Technology / Case number: #21685
Hyuckjin Kwon / Jongyoon Han
Technology Areas: Agriculture & Food / Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Synthetic Medical Image Generation

Technology / Case number: #21698
Elazer R Edelman / Max Olender
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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