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Functionalization of Protective Antigen by Chemical Conjugation

Technology / Case number: #20802
Bradley L. Pentelute / Zeyu Lu
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Composition and Methods to Generate Assymetric Bispecific Antibodies from a Single Cell Line

Technology / Case number: #17698
Ram Sasisekharan / Andrew Hatas / Eduardo Fleischer / Vidya Subramanian / Kannan Tharakaraman
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Amphiphilic Cisplatin Prodrug Nanoparticles for Co-Incorporation of Water-Insoluble Synergistic Small Molecules Chemotherapies and RNAi

Technology / Case number: #17774
Paiman Ghoroghchian / Ting Li / Ruogu Qi / Haihua Xiao
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Selective Metal-Mediated Arylation of Dichalcogenides in Biomolecules

Technology / Case number: #17814
Stephen Buchwald / Daniel Cohen / Chi Zhang / Bradley L. Pentelute
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Transcriptional Sensor for Bile Acids in Bacteroides Thetaiotaomicron

Technology / Case number: #18573
Christopher Voigt / Mao Taketani
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Platinum-Anthracycline Derivative Conjugates and Their Therapeutic Applications

Technology / Case number: #20922
Stephen J Lippard / Jonathan Braverman / Fang Wang / Omer Yilmaz
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Convergent and Biomimetic Enantioselective Total Synthesis of (-)-Communesin F

Technology / Case number: #18676
Mo Movassaghi / Wen-Tau Chang / Matthew Pompeo / Stephen Lathrop
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Intraperitoneal Injection of Nanoparticles Results in Near Perfect Localization Within Peritoneal Tumor Deposits

Technology / Case number: #19352
Angela Belcher / Zhimin Tao / Paiman Ghoroghchian / Xiangnan Dang
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Identification and Application of Ketogenic Properties of Intestinal Stem Cell

Technology / Case number: #20090
George Eng / Fang Wang / Chia-Wei Cheng / Omer Yilmaz
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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A Nanoscale Interface for Cross-modal Medical Imaging

Technology / Case number: #20367
Robert Langer / Aviad Hai / Virginia Spanoudaki / Alan Pradip Jasanoff / Daniel Anderson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Machine-Vision Guided Microscopy for Autonomous Characterization of Quantum Emitters and Photonic Nanostructures

Technology / Case number: #19312
Dirk R Englund / Michael Walsh
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Electronics & Photonics
Impact Areas: Healthy Living, Advanced Materials
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Method of Simulating Chemical Reactions

Technology / Case number: #19748
Klavs F. Jensen / Wengong Jin / Connor Wilson Coley / Tommi S Jaakkola / Regina Barzilay
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Sustainable Future
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Behavior-Based Robot Programming

Technology / Case number: #18810
Neville Hogan / Lucille Hosford
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation
Impact Areas: Connected World
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Method for Identifying Noise Sources in Quantum Systems via Multi-Level Noise Spectroscopy

Technology / Case number: #21722
William Oliver / Simon Gustavsson / Jochen Braumueller / Antti Pekka Vepsalainen / Youngkyu Sung
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Sensing & Imaging
Impact Areas: Advanced Materials
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General Unitary Neural Network

Technology / Case number: #19158
Marin Soljacic / Max Tegmark / John Peurifoy / Li Jing / Tena Dubcek Varga / Yichen Shen / Scott Skirlo
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Uncharted Frontiers, Connected World
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Small Molecule Binders of the Oncogenic Fusion Transcription Factor PAX3-FOXO1

Technology / Case number: #23850J
Angela Koehler / Marco Wachtel / Beat Schaefer / Madeleine Henley / Becky Leifer / Shelby Doyle
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Metal-Organic Frameworks Mediated Macromolecule Delivery System

Technology / Case number: #22862J
Robert Langer / Xiaoyue Qi / Adam Wentworth / Giovanni Traverso
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Novel Small Molecule Modulators of Myb-Mediated Transcription with Potential Use for Cancer Therapy

Technology / Case number: #22044
Angela Koehler / Jasmin Kruell / Brice Curtin / Florian Kabinger / Becky Leifer
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Predicting Native Language from Gaze

Technology / Case number: #19818
Boris Katz / Yevgeni Berzak
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science / Sensing & Imaging
Impact Areas: Uncharted Frontiers, Connected World
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A Platform for Continuous Directed Evolution in Human Cells

Technology / Case number: #19909
Matthew D. Shoulders / Samuel Hendel / Chet Berman / Christopher Moore / Louis Papa
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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