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Small Molecule Inhibitors of Interleukin-4

Technology / Case number: #22186J
Angela Koehler / Sean Quinnell / Daniel Sheehy / Luke Ceo / Kelly Tan / Stephen Nestor / Becky Leifer / Shelby Doyle / Arturo Vegas
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Chimeric Degraders of Cyclin Dependent Kinase 9 with Potential Use for Cancer Therapy

Technology / Case number: #22028
Angela Koehler / Mohammed Toure / Florian Kabinger / Julie Urgiles / Andre Richters
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Hybrid Materials with Living Cells and Tough Hydrogels

Technology / Case number: #18548
Timothy K Lu / Tzu-Chieh Tang / Xinyue Liu / Eleonore Tham / Xuanhe Zhao
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Pooled Screening Identifies Genomic Features (Biomarkers) Modulating Nanoparticle-Cell Interactions

Technology / Case number: #22785J
Paula Hammond / Joelle Straehla / Natalie Boehnke / Angela Koehler
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Cationic Lipidoids and Their Uses for Immunotherapy

Technology / Case number: #19803
Daniel Anderson / Lei Miao / Yuxuan Huang / Linxian Li
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Synthesis of Ester, Carbonate, and Carbamate-derived Novel Biodegradable Ionizable Lipids from Methyl Ricinoleate or Methyl 12-Hydroxystearate and its Applications

Technology / Case number: #23381Q
Daniel Anderson / Jacob Witten / rajith manan / Akiva Gordon / Bowen Li / Luke Rhym
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Spatially Localized Gene Delivery of Adeno-Associated Viruses

Technology / Case number: #25055
Polina Anikeeva / Keisuke Nagao
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Attention Maps

Technology / Case number: #18155QJ
Bryan Reimer / Bobbie Seppelt / Linda Angell / Andres Munoz Delgado / Joonbum Lee / Bruce L Mehler / Joseph Coughlin
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Sensing & Imaging
Impact Areas: Healthy Living, Connected World
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A Software System to Synthetically Generate Test Data for Testing Large Scale Software Applications

Technology / Case number: #18981J
Kalyan Veeramachaneni / Sunder Nochilur / Kishore Durg / Jeffery Wilkinson / Neha Patki
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Uncharted Frontiers
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Lipid Anchorage of Cytokines onto Layer-by-Layer Nanoparticles

Technology / Case number: #25070H
Darrell J Irvine / Ivan Pires / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Clockwise Learning Task

Technology / Case number: #25128M
Ann M. Graybiel / Georgios Papageorgiou
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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Cell-Surface Anchored Cytokine Therapy

Technology, Tangible Property / Case number: #25245H
Darrell J Irvine / Luciano Santollani / Karl Dane Wittrup
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Engineered Synthetic IRES with Improved and Robust Translation in Circular RNA

Technology / Case number: #25300YJ
James Collins / Nayoung Kim / Yu Li / Makoto Lalwani / Xiaoyu Chen / Kehan Zhang / Shiva Razavi / Katherine Ilia
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Reconstituted Lipoprotein Particles to Rescue Lipid Defects in the Alzheimer's Brain

Technology / Case number: #25445P
Li-Huei Tsai / Rebecca Pinals
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Method of Enhanced Clearance of Uremic Toxins in Hemodialysis using Nanoporous Membranes

Technology / Case number: #21853
Rohit N Karnik / Chi Cheng / Chun Man Chow / Aaron Persad
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Deep Context Maps

Technology / Case number: #22949
Daniela Rus / Arjun Gupta / Igor Gilitschenski / Sertac Karaman / Guy Rosman
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Sensing & Imaging
Impact Areas: Healthy Living, Connected World
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Scalable Ultra Low Latency Photonic Tensor Processor

Technology / Case number: #23088
Dirk R Englund / Alexander Sludds / Liane Sarah Bel Bernstein
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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Optimized Alum-Anchored HIV Env Immunogens

Technology / Case number: #24972HJ
Darrell J Irvine / William Schief / Jon Steichen / Christopher Cottrell / Kristen Rodrigues
Technology Areas: Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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High Coherence, Small Footprint Superconducting Qubit made by Stacking up Atomically Thin Crystals

Technology / Case number: #21842
William Oliver / Joel IJ Wang / Simon Gustavsson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Electronics & Photonics
Impact Areas: Uncharted Frontiers, Advanced Materials
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Translational Hearing Aides for Older Adults

Technology / Case number: #24962
Harry Asada / Ravi Tejwani
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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