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Invention Disclosure: Kinetic Sensing, Signal Generation, Feature Extraction, and Pattern Recognition for Control of Autonomous Wearable Leg Devices

Technology / Case number: #18945TE
Luke Mooney / Matthew Carney / Roman Stolyarov / Cameron Taylor / Hugh Herr
Technology Areas: Biotechnology / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Transdermal Optogenetic Peripheral Nerve Stimulation

Technology / Case number: #18928TE
Anthony Zorzos / Benjamin Maimon / Hugh Herr
Technology Areas: Biotechnology
Impact Areas: Healthy Living, Uncharted Frontiers
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Neural Efferent and Afferent Control of Spring Equilibrium, Damping, and Power in Backdrivable and Non-Backdrivable Series-Elastic Actuators Comprising Variable Series Stiffness Mechanisms

Technology / Case number: #20960TE
Matthew Carney / Roman Stolyarov / Emily Rogers-Bradley / Seong Ho Yeon / Hugh Herr
Technology Areas: Biotechnology / Computer Science / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Optimized Opsin Trafficking with Fluorescence-Dead Protein Fusions

Technology / Case number: #18783TE
Edward Boyden / Kiryl Piatkevich / Aimei Yang / Demian Park
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Dynamic Single-Cell Fragility Test that Assesses Red Blood Cell Membrane Integrity with Applications to Stored Blood

Technology / Case number: #25732
Fang Kong / Subra Suresh / Ming Dao
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Stretchable, Wearable Ultrasound Transducer for Wide-Scale Breast Cancer Data Collection

Technology / Case number: #20934TE
Canan Dagdeviren / Lin Zhang
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Tri-Functional Hydrophilic Self-Crosslinked Dimethylacrylamide Polymer

Technology / Case number: #18698TEM
Edward Boyden / Linyi Gao / Ruixuan Gao / Nikita Obidin
Technology Areas: Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Neuromechanical Interventions for the Mitigation of Limb Pathology

Technology / Case number: #18430TE
Anthony Zorzos / Benjamin Maimon / Matthew Carty / Tyler Clites / Jean-Francois Duval / Shriya Srinivasan / Hugh Herr
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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A Microphysiological Model of the Brain Including Blood-brain Barrier, Neural Tissue and Meningeal Lymphatics

Technology / Case number: #24291
Roger Kamm / Giovanni Offeddu / Shun Zhang / Marie Floryan / Georgios Pavlou / Cynthia Hajal / Sarah Spitz / Jean Serrano Flores / Eunkyung Ko / Yoojin Shin / Xun Wang
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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A Fully Differential Piezoelectric Microphone and Amplifier System for Cochlear Implants and Other Hearing Devices

Technology / Case number: #23776JQ
Hideko Nakajima / Aaron Yeiser / Elizabeth Olson / Lukas Graf / Christopher McHugh / Ioannis Kymissis / Jeffrey Lang
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Closed-Loop Intramuscular Motility Prosthesis, Submucosal Neuromodulation Device and Minimally Invasive Endoscopic Implantation Tool

Technology / Case number: #23258J
Polina Anikeeva / Carlo Giovanni Traverso / Shriya Srinivasan / Robert Langer / Marc-Joseph Antonini
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
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Device and Method for Imaging Shortwave Infrared Autofluorescence

Technology / Case number: #18527J
Oliver Bruns / Jessica Carr / Klaus Van Leyen / Yi Zheng / Marianne Aellen / Moungi Bawendi
Technology Areas: Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Hybrid Materials with Living Cells and Tough Hydrogels

Technology / Case number: #18548
Timothy Lu / Xuanhe Zhao / Eleonore Tham / Xinyue Liu / Tzu-Chieh Tang
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Diagnostics / Therapeutics
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Pooled Screening Identifies Genomic Features (Biomarkers) Modulating Nanoparticle-Cell Interactions

Technology / Case number: #22785J
Angela Koehler / Natalie Boehnke / Joelle Straehla / Paula Hammond
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
License

Ultrastructural Membrane Expansion Microscopy

Technology / Case number: #25088HM
Edward Boyden / Tay Won Shin
Technology Areas: Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
License

Variable Compression Human-Machine Interface Cuff

Technology / Case number: #21776
Meghan Huber / James Hermus / Gabrielle Enns / Neville Hogan
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Articulated and Extra Robotic Limbs for Stability and Load Support During Crawling, Standing, Walking, and Climbing

Technology / Case number: #19754
Daniel Gonzalez / Haruhiko Asada
Technology Areas: Biotechnology / Industrial Engineering & Automation
Impact Areas: Healthy Living, Uncharted Frontiers
License

3D Structured Electromechanical Adhesive Surfaces for Dexterous Gripping

Technology / Case number: #19561
Sanha Kim / Anastasios Hart
Technology Areas: Biotechnology / Industrial Engineering & Automation
Impact Areas: Advanced Materials
License

Near and Shortwave Infrared Polymethine Dyes

Technology / Case number: #19474
Ellen Sletten / Justin Caram / Timothy Swager
Technology Areas: Diagnostics / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
License

Method for Point-of-use Testing for Bacteriological Water Contamination in Resource-Limited Environments

Technology / Case number: #19080
Rohit Karnik / Emily Hanhauser / Michael Bono / Chintan Vaishnav / Sydney Beasley / Anastasios Hart
Technology Areas: Biotechnology / Diagnostics / Environmental Engineering / Sensing & Imaging
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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