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Method for Screening Libraries of Enzymes with Improved Catalytic Properties or Altered Substrate Specificity Using Microwells for the Spatial Separation of Cells Producing the Enzymes

Exclusively Licensed Technology / Case number: #12967WJ
Kerry Love / J. Christopher Love
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living

Brushed Prodrugs and Uses Thereof

Exclusively Licensed Technology / Case number: #21834
Jeremiah A. Johnson / Hung Nguyen / Yivan Jiang
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Single-Cell Collection Downstream of Biophysical Measurements

Exclusively Licensed Technology / Case number: #19237
Scott Manalis / Mark Stevens / Nicholas Calistri / Robert Kimmerling / Selim Olcum
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living

Biomimetic Robotic Leg with Agonist-Antagonist Actuation

Exclusively Licensed Technology / Case number: #13611TE
Hugh M Herr / Patricia Ellis / Ernesto Martinez-Villalpando / Michael Eilenberg / Jeff Weber / Hartmut Geyer
Technology Areas: Biotechnology / Industrial Engineering & Automation
Impact Areas: Healthy Living

Iterative Direct Expansion Microscopy

Non-Exclusively Licensed Technology / Case number: #20861TEM
Edward Stuart Boyden / Jinyoung Kang / Deblina Sarkar / Asmamaw Wassie
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Multi-Layered Injectable Self-Assembling Peptide Scaffold Hydrogels for Long-Term Sustained Release of Human Antibodies

Exclusively Licensed Technology / Case number: #15537XE
Shuguang Zhang / Sotirios Koutsopoulos
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

Biomaterials for Enhanced Implant-Host Integration

Exclusively Licensed Technology / Case number: #22709HJQ
Christopher Chen / Michael Yang / Ritika Chaturvedi / Jan Baranski / Kelly Stevens / Sangeeta Bhatia
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials

Nanoscale Imaging of Proteins and Nucleic Acids via Expansion Microscopy

Non-Exclusively Licensed Technology / Case number: #18127TEYJQ
Edward Stuart Boyden / Shahar Alon / Evan Daugharthy / Fei Chen / Asmamaw Wassie / George Church
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
License

Bioadhesive with Triggerable On-Demand Detachment

Exclusively Licensed Technology / Case number: #22423
Xuanhe Zhao / Xiaoyu Chen / Hyunwoo Yuk
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

Novel RNA Modality for Translation in Eukaryotic Cells

Exclusively Licensed Technology / Case number: #19874Q
Daniel Anderson / Robert Wesselhoeft / Piotr Kowalski
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

A Biosensor and Method Based on Magnetic Resonance Relaxometry

Exclusively Licensed Technology / Case number: #14651DE
Jongyoon Han / Lan Chen / Weng Kung Peng
Technology Areas: Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living

SEEDs (in Situ Expansion of Engineered Devices) for Templated Regeneration

Exclusively Licensed Technology / Case number: #18069HJQ
Christopher Chen / Kelly Stevens / Sangeeta Bhatia
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living

Microbial Production of Glucaric Acid

Exclusively Licensed Technology / Case number: #13147
Tae Moon / Sang Hwal Yoon / Kristala L Jones Prather
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living

System and Method for Sepsis Care Task Management

Exclusively Licensed Technology / Case number: #17662JQ
Andrew Reisner / Michael Filbin / Thomas Heldt
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science
Impact Areas: Healthy Living, Connected World

Devices and Methods for Non-Invasive Hematological Measurements

Exclusively Licensed Technology / Case number: #18366J
Maria Jesus Ledesma Carbayo / Tom Vettenburg / Alberto Pablo Trinidad / Jason Tucker-Schwartz / Luis Soenksen Martinez / Aurelien Bourquard / Carlos Castro Gonzalez / Ian Butterworth / Alvaro Sanchez Ferro
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living

Intravesical Drug Delivery Device with a Retention Feature

Exclusively Licensed Technology / Case number: #12988
Michael Cima / Heejin Lee
Technology Areas: Biotechnology / Drug Delivery
Impact Areas: Healthy Living

Biomimetic Motion and Balance Controllers

Exclusively Licensed Technology / Case number: #11795TEQ
Hugh M Herr / Patricia Ellis / Marko Popovic / Andreas Hofmann
Technology Areas: Biotechnology / Industrial Engineering & Automation
Impact Areas: Healthy Living, Advanced Materials

Magnetic Resonance Relaxometry (MRR) Measurement to Predict Chondrogenic Potential of Mesenchymal Stem Cells (MSCs)

Exclusively Licensed Technology / Case number: #24080DEJ
Jongyoon Han / Dahou Yang / Eng Lee / Yingnan Wu / Zheng Yang
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living

Device for Controlled Apical Flow in Hanging Cell Culture Inserts

Non-Exclusively Licensed Technology / Case number: #18185JQ
Linda Griffith / Rebecca Carrier / Emily Suter / Collin Edington / Transon Nguyen / David L Trumper
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

In Situ Curing Hydrophobic Tissue Adhesive

Exclusively Licensed Technology / Case number: #16181J
Robert Langer / Yuhan Lee / Nora Lang / Maria Jose Pereira / Pedro Del Nido / Jeffrey Michael Karp
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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