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Analysis and Design of a Membrane-based Triggering Mechanism for Ingestible Devices

Technology / Case number: #22043
Carlo Giovanni Traverso / Graham Arrick / Torben Sebastia Last
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Manually Actuated Device Capable of On-demand/Programmed Pulsatile Drug Delivery

Technology / Case number: #21833JQ
Carlo Giovanni Traverso / Jason Li / Rebecca McManus / Seungho Lee / Adam Wentworth / Qianqian Wan
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Machine Learning for the Design of Cancer Vaccine Adjuvants

Technology / Case number: #21680J
Carlo Giovanni Traverso / Ameya Kirtane / Daniel Reker / Robert Langer / Lewis Scott Jones / Hyunjoon Kim / Netra Rajesh
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Multi-stable Device Configurations and Controls for Gastric Drug Delivery Devices

Technology / Case number: #22017J
Carlo Giovanni Traverso / Niclas Roxhed / Robert Langer / Morten Frederiksen / Jacob Wainer / Brian Mouridsen / Jesper Windum / Declan Gwynne / Graham Arrick / Yi Lu / Torben Sebastia Last / Adam Jun Bohr / Nikolaj Eusebius Jakobsen / Kuldeep Sanger / Jens Laursen / Ludwig Erik Aguilar
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Flexible Electronics for Analyte Detection

Technology / Case number: #21994J
Carlo Giovanni Traverso / Robert Langer / Hen Wei Huang / Siheng You / Luca Di Tizio
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Flower-Inspired System with Shape-Memory Torsion Springs

Technology / Case number: #20940J
Carlo Giovanni Traverso / Ester Caffarel Salvador / Robert Langer / Sahab Babaee / Simo Pajovic
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Biodegradable Polymers for Messenger RNA Delivery to the Lung

Technology / Case number: #19314
Kevin Kauffman / James Kaczmarek / Asha Patel / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Structure-Guided Chemical Modification of Guide RNA and its Applications

Technology / Case number: #19175V
Hao Yin / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Gene Delivery Carrier

Technology / Case number: #19091J
Umberto Palmiero / James Kaczmarek / Davide Moscatelli / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Advanced Materials
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Derivation of Enteroendocrine Cells and Insulin Expressing Cells

Technology / Case number: #18445J
Jeffrey Karp / Xiaolei Yin / Robert Langer
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Crystalline and Amorphous Formulations Used to Deliver Anti-Fibrotic (and other) Compounds in Conjunction with Implanted Materials (Cells/Devices)

Technology / Case number: #18287J
Joshua Doloff / Shady Farah / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
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Anti-Zika Virus Antibodies

Technology / Case number: #18525J
Kannan Tharakaraman / Eng Ooi / Kuan Chan / Satoru Watanabe / Subhash Vasudevan / Ram Sasisekharan
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Motorized and Balloon Dynamic Satiety Stimulator

Technology / Case number: #25050J
Carlo Giovanni Traverso / Neil Jia
Technology Areas: Biotechnology / Industrial Engineering & Automation
Impact Areas: Healthy Living
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A Fully Implantable, Autonomous Closed-Loop System Capable of Long-Term Vital Signs Monitoring and Performing Lifesaving Treatment

Technology / Case number: #23387J
Carlo Giovanni Traverso / Hen Wei Huang / Seungho Lee / Saurav Maji / Peter Chai / Tom Kerssemakers / Ian Ballinger / Anantha Chandrakasan
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Computer Science / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
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A Graph Approach for Protein Structure Prediction via Machine Learning based Correction

Technology / Case number: #24267J
Markus Buehler / Benedetto Marelli / Pin-Yu Chen / Lingfei Wu / Siyu Huo / Federica Rigoldi / Kai Guo
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science
Impact Areas: Healthy Living
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DNA Based Immobilization for Improved Electrochemical Carbon Dioxide Reduction

Technology / Case number: #23961
Ariel Furst / Gang Fan
Technology Areas: Biotechnology / Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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Ionizable Lipids for Messenger RNA Delivery

Technology, Tangible Property / Case number: #24861
Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Thermo-Responsive, Inflammation-Targeting (TRIT) Hydrogel Formulations for Local Drug Delivery in Intestinal Inflammation

Technology / Case number: #19181J
Carlo Giovanni Traverso / Sufeng Zhang / Ashok Kakkar / Joshua Korzenik / Robert Langer
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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A Generalizable, High-Throughput Method to Rapidly add Chemical Moieties to a Small Molecule Library

Technology / Case number: #22196J
Angela Koehler / Brice Curtin / Jasmin Kruell / Catherine Henry / Sebastian Pomplun / Christina Woo / Chia-fu Chang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Small Molecule Inhibitors of Interleukin-4

Technology / Case number: #22186
Angela Koehler / Arturo Vegas / Shelby Doyle / Becky Leifer / Sean Quinnell / Stephen Nestor / Kelly Tan / Luke Ceo / Daniel Sheehy
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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