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Biomarkers and Therapeutics for Autism Spectrum Disorders

Technology / Case number: #13589P
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Method for High Efficiency in Vivo Gene Editing

Technology / Case number: #17117H
Tyler Jacks / Hao Yin / Joseph Dorkin / Wen Xue / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Programmable Drug Delivery Profiles of Tumor-Targeted Bacteria

Technology / Case number: #15818H
Sangeeta Bhatia / Tal Danino
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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High-Throughput Screening Metabolic Flux Biosensor

Technology / Case number: #16813JW
Gerald Fink / Jose Avalos / Gregory Stephanopoulos
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Epigenetic Mechanisms Re-Establish Access to Long-Term Memory After Neuronal Loss

Technology / Case number: #12467HPBJ
Stephen Haggarty / Li-Huei Tsai
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Synthesis of a New Biopolymer for Precision Agriculture

Technology / Case number: #25699
Benedetto Marelli / Giorgio Rizzo
Technology Areas: Agriculture & Food / Chemicals & Materials
Impact Areas: Healthy Living
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A Single-Walled Carbon Nano-Tube/Chitosan Hydrogel Array for the Label-Free, Optical Detection of Protein-Protein Interactions

Technology / Case number: #14201
Michael S. Strano / Nigel Reuel / Jin Ho Ahn / Paul Barone
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Genomic Editing with Site- Specific Retrotransposons

Technology / Case number: #25220
Omar Abudayyeh / Christopher Fell / Justin Lim / Lukas Villiger / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Cystic Fibrosis Correction with Programmable Genomic Editing

Technology / Case number: #24666
Omar Abudayyeh / Christopher Fell / Matthew Yarnall / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Gas Sensors Based Upon Metal Macrocycle-Carbon Composites

Technology / Case number: #16884
Timothy Manning Swager / Graham Sazama / Sophie Liu / Alexander Petty / Jan Schnorr
Technology Areas: Agriculture & Food / Energy & Distribution / Sensing & Imaging
Impact Areas: Sustainable Future
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Thiol-yne Mediated Synthesis of Multi-Tailed Lipids for siRNA Delivery

Technology / Case number: #15846
Robert Langer / Akinleye Alabi / Kevin Love / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Develop New Lethal Mutagens for Viral Diseases

Technology / Case number: #16089
John M Essigmann / Katherine Silvestre / Deyu Li
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Ligand-Inducible Post-Transcriptional Gene Regulation Using Protein-Binding RNA Aptamers

Technology / Case number: #13998J
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Fast Nonlinear Dynamic Electrochemical Characterization of Arbitrary Fluids

Technology / Case number: #24656
Ian Hunter / Billal Iqbal / Kimberley Cheng / Michael Aling
Technology Areas: Agriculture & Food / Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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One-Step Construction of Allogeneic CAR-NK Cells with Increased Anti-Tumor Cytotoxicity and Resistant to Rejection by Host T Cells and NK Cells

Technology / Case number: #25757J
Jianzhu Chen / Fuguo Liu / Rizwan Romee
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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RNA Degradation-based Toggle Switch

Technology / Case number: #21622
Ron Weiss / Noreen Wauford / Breanna DiAndreth
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Modular MicroRNA Expression from Self-Replicating RNA (Replicons)

Technology / Case number: #25464
Ron Weiss / Tea Crnkovic
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Production of Stable Non-Polyadenylated RNAs

Technology / Case number: #15860
Phillip Sharp / Jeremy Wilusz
Technology Areas: Biotechnology / Drug Delivery
Impact Areas: Healthy Living
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Nanofluidic Sorting System for Gene Synthesis & PCR Reaction Products

Technology / Case number: #15517L
Peter Carr / Tarun Jain / Carlos Aguilar / Rohit N Karnik
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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Single-Step Insertion into Repeated Regions for Efficient Multi-Locus Assortment and Daisyfield Drive

Technology / Case number: #19136TJE
Kevin Esvelt / Charleston Noble / Jianghong Min
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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