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Rapid Droplet-Based Systems for Antibody Drug Discovery

Technology / Case number: #23890J
Brandon DeKosky / Shuyan Jin / Nicoleen Boyle / Ahmed Fahad / Cheng-yu Chung / Matias Gutierrez Gonzalez
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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High-throughput Electroporation Device

Technology / Case number: #21871
Cullen R. Buie / Sijie Chen / Po-Hsun Huang
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Brain-Computer Interface for User's Visual Focus Detection

Technology / Case number: #20246
Sanjay Emani Sarma / Alexandre Armengol Urpi
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology
Impact Areas: Healthy Living, Uncharted Frontiers, Connected World
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Multi-Targeted, Tunable, Sustained Delivery of Drugs and Other Payloads to Charged Avascular Tissues

Technology / Case number: #21303
Alan Grodzinsky / Yamini Krishnan
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Purification of Substances Using CO2 Sub-and Super-Critical Fluid Chromatography

Technology / Case number: #19742
Clark Colton / John MacKay / Truong Cai / Tony Elian / Mariya Layurova / Veronica Wilson / John Moses / William Dalzell
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Sustainable Future
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Single Cell Super-Resolution Proteomics

Technology / Case number: #24088
Mark Harnett / Dimitra Vardalaki
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living, Uncharted Frontiers
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Targeting Dendritic Cell Lectins with Glycosylated Particles Containing TLR Ligands Facilitates Efficient Immune Responses

Technology / Case number: #24570J
Laura L Kiessling / Robert Hincapie / Mohammad Murshid Alam / M.G. Finn / Valerie Lensch
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Cyclooctynes for Click Chemistry

Technology / Case number: #23210
Ronald T Raines / Brian Gold / Nile Abularrage / Jesús Dones / Brian Graham
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Uncharted Frontiers, Sustainable Future, Advanced Materials
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Synthetic Mucin Glycans as Antifungal Agents

Technology / Case number: #24073J
Katharina Ribbeck / Rachel Hevey / Julie Takagi
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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Synthesis of Covalent Protein Dimers that can Inhibit MYC-Driven Transcription

Technology / Case number: #23305WJ
Stephen Buchwald / Charles Li / Susana Hawken / Ann Boija / Muhammad Jbara / Jacob Rodriguez / Andrei Loas / Sebastian Pomplun / Carly Schissel / Isaac Klein / Bradley L. Pentelute
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Targeting Lung Microbiota and its Responding Immune Pathways for Lung Cancer Treatment

Technology / Case number: #20602HRJ
Tyler Jacks / Georgia Lagoudas / Chengcheng Jin / Paul Blainey
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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RNA-Loaded Lipid Nanoparticle (LNP)

Technology, Tangible Property / Case number: #24973H
Darrell J Irvine / B.j. Kim
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Target for Modulating Body Mass

Technology / Case number: #21326
Jianzhu Chen / Ting Dong / Yingzhong Li / Nikola Ivica
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Composition and Methods to Generate Assymetric Bispecific Antibodies from a Single Cell Line

Technology / Case number: #17698
Ram Sasisekharan / Andrew Hatas / Eduardo Fleischer / Vidya Subramanian / Kannan Tharakaraman
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Amphiphilic Cisplatin Prodrug Nanoparticles for Co-Incorporation of Water-Insoluble Synergistic Small Molecules Chemotherapies and RNAi

Technology / Case number: #17774
Paiman Ghoroghchian / Ting Li / Ruogu Qi / Haihua Xiao
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Selective Metal-Mediated Arylation of Dichalcogenides in Biomolecules

Technology / Case number: #17814
Stephen Buchwald / Daniel Cohen / Chi Zhang / Bradley L. Pentelute
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Optical Methods Level Sensor for Use in a Bioreactor

Technology / Case number: #19143
J. Christopher Love / Amos Lu / Craig Mascarenhas / Richard D Braatz
Technology Areas: Biotechnology
Impact Areas: Healthy Living
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Platform for High-Resolution Genome Mapping

Technology / Case number: #19244
Rajeev Ram / Huaiyu Meng
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Electronics & Photonics
Impact Areas: Healthy Living
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Compact Proton Beam Energy Modulator

Technology / Case number: #19382
Matthew Cavuto / Melissa Li / Nathaniel Rodman / Neerja Aggarwal
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Single-Sided Magnets for Remote NMR Measurements

Technology / Case number: #19511
Michael Cima / Ashvin Bashyam / Matthew Li
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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