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Tuning Chloroplast Transgene Expression from Synthetic Operon

Technology / Case number: #25494
Christopher Voigt / Qiguo Yu
Technology Areas: Agriculture & Food / Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Lung-Cancer Specific T Cell Dysfunction

Technology / Case number: #23004
Karl Dane Wittrup / Duncan Morgan / Brendan Horton / Stefani Spranger / J. Christopher Love
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Augmentation of T and B Cell Activation with a Novel Cysteine Protease Linker Sequence

Technology / Case number: #25338
Tyler Jacks / Sean-Luc Shanahan
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Compositions for the Conditional Delivery of Macromolecules and Combination Therapeutics

Technology / Case number: #24492H
Sangeeta Bhatia / Qian Zhong / Edward Tan / Chayanon Ngambenjawong
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Control Replication and Transcription of Self-Replicating RNA in Responses to Small Molecule TMP

Technology / Case number: #22331H
Darrell J Irvine / Parisa Yousefpour / Jan Lonzaric / Yingzhong Li / Ron Weiss
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Catheter for Intracardiac 3D Bioprinting

Technology / Case number: #22338J
Brett E Bouma / Markus Horvath / Sophie Wang / Milen Shishkov / Victor Damptey / Connor Verheyen / Keegan Mendez / Ellen Roche / Sebastien Uzel / Jennifer Lewis
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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M13 Bacteriophage with a High Cysteine Content and Genetically Engineerable Hydrogels

Technology / Case number: #22369
Angela Belcher / Nimrod Heldman / William Records
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Split Intein-based Selection for Modified Peptide Binders to SARS-CoV-2 Spike Protein

Technology / Case number: #22502
Christopher Voigt / Andrew King / Emerson Glassey
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Compositions of Polypeptides for Subunit Vaccines for SARS-CoV-2

Technology / Case number: #22703
J. Christopher Love / Sergio Rodriguez / Neil Dalvie
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Fusion Capsid Therapy for COVID-19 and Applies to Other Viruses: Universal "Dominant" Antiviral to Prevent Virus Evolution and Future Pandemics (DNA/RNA/Protein)

Technology, Tangible Property / Case number: #22801MH
Robert Langer / Bowen Li / Yong Qian / Alexi Choueiri / Edward Stuart Boyden / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Novel Peptides to Inhibit Ena/VASP Proteins

Technology / Case number: #22897J
Amy Keating / Samantha Hill / Ghassan Mouneimne / Sara Parker / Meucci IIunga / Theresa Hwang
Technology Areas: Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Lectin Fingerprinting for Mapping Viral Glycosylation and Identifying Neutralizing Antibodies

Technology / Case number: #22955
Laura L Kiessling / Amanda Dugan / Michael Wuo
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Interfacial Bioconjugation on Emulsion Droplets

Technology / Case number: #20314
Timothy Manning Swager / Qifan Zhang
Technology Areas: Chemicals & Materials / Drug Delivery / Sensing & Imaging
Impact Areas: Advanced Materials
License

Multi-Targeted, Tunable, Sustained Delivery of Drugs and Other Payloads to Charged Avascular Tissues

Technology / Case number: #21303
Alan Grodzinsky / Yamini Krishnan
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Targeting Dendritic Cell Lectins with Glycosylated Particles Containing TLR Ligands Facilitates Efficient Immune Responses

Technology / Case number: #24570J
Laura L Kiessling / Robert Hincapie / Mohammad Murshid Alam / M.G. Finn / Valerie Lensch
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Synthetic Mucin Glycans as Antifungal Agents

Technology / Case number: #24073J
Katharina Ribbeck / Rachel Hevey / Julie Takagi
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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Synthesis of Covalent Protein Dimers that can Inhibit MYC-Driven Transcription

Technology / Case number: #23305WJ
Stephen Buchwald / Charles Li / Susana Hawken / Ann Boija / Muhammad Jbara / Jacob Rodriguez / Andrei Loas / Sebastian Pomplun / Carly Schissel / Isaac Klein / Bradley L. Pentelute
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Targeting Lung Microbiota and its Responding Immune Pathways for Lung Cancer Treatment

Technology / Case number: #20602HRJ
Tyler Jacks / Georgia Lagoudas / Chengcheng Jin / Paul Blainey
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
License

RNA-Loaded Lipid Nanoparticle (LNP)

Technology, Tangible Property / Case number: #24973H
Darrell J Irvine / B.j. Kim
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Target for Modulating Body Mass

Technology / Case number: #21326
Jianzhu Chen / Ting Dong / Yingzhong Li / Nikola Ivica
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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