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A Computational Method for Identifying the Biophysical Interactions that Determine Human T Cell Specificity from Structural Data and Primary Amino Acid Sequences

Technology / Case number: #26026J
Xingcheng Lin / Jason George / Ailun Wang / José Onuchic / Herbert Levine
Technology Areas: Computer Science / Therapeutics
Impact Areas: Healthy Living
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Mucin-Inspired Glycopolypeptides for Managing Microbial Infections

Technology / Case number: #26189J
Katharina Ribbeck / Jessica Kramer / Michaela Gold / Kelsey Wheeler
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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CD80 is a Biomarker of p53 Activity and a Target for Cancer Therapy

Technology / Case number: #15386H
Tyler Jacks / Leah Schmidt / David Feldser
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Polyamine-Fatty Acid Derived Lipidoids for Drug Delivery

Technology / Case number: #16367
Daniel Anderson / Rebecca McClellan / Owen Fenton / Joseph Dorkin
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Valency Controlled Quantum Dots with Tunable Number of Biotin Binding Sites

Technology / Case number: #12606B
Moungi G Bawendi / Wenhao Liu / Mark Howarth / Alice Ting
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Electronics & Photonics / Therapeutics
Impact Areas: Healthy Living
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Methods and Compositions for Protein Labeling Using Lipoic Acid Ligases

Technology / Case number: #12773
Alice Ting / Marta Fernandez Suarez / Yoon-Aa Choi / Hemanta Baruah
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Self-Assembling Peptides Incorporating Modifications and Methods of Use Thereof

Technology / Case number: #13846XE
Shuguang Zhang / Yoshiyuki Kumada
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
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A Mitochondria Targeting Platinum(IV) Complex with Dual Cell Killing Modes

Technology / Case number: #13271
Stephen J Lippard / Shanta Dhar
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Formulation of Polymeric Particles for Prostate Cancer Targeting

Technology / Case number: #12162J
Robert Langer / Stephen Zale / Benjamin Teply / Jianjun Cheng / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Antigenically Intact Hemagglutinin in Circulating Avian and Swine Influenza Viruses and Potential for H3N2 Pandemic

Technology / Case number: #16225
Rahul Raman / Kannan Tharakaraman / Ram Sasisekharan
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Immune Pharmacytes: Nanoparticle-Modified Leukocytes for Immunotherapy

Technology / Case number: #13509H
Darrell J Irvine / Anna Bershteyn / Jae Hyun (James) Moon / Matthias Stephan
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Identification of Mitochondrial GABA Transporter

Technology / Case number: #26187
Matthew Vander Heiden / Samuel Block
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Metakaryocides for Treatment of Cancers and Other Diseases with Metakaryotic Stem Cells

Technology / Case number: #15279
William Thilly / Elena Gostjeva
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Protein Retrosplicing Enabled by a Double Ligation Reaction

Technology / Case number: #15368
Bradley L. Pentelute / Rocco Policarpo / Jingjing Ling / Amy Rabideau / Xiaoli Liao
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Engineered Probiotics for Urinary Cancer Diagnosis

Technology / Case number: #15881HJ
Sangeeta Bhatia / Jeff Hasty / Arthur Prindle / Tal Danino
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Methods for Treating Polycystic Kidney Disease

Technology / Case number: #16389J
John M Essigmann / Stefan Somlo / Sorin Fedeles / Bogdan I Fedeles / Robert Croy
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Single Wall Carbon Nanotubes as In Vivo Sensors

Technology / Case number: #16531
Michael S. Strano / Nicole Iverson / Thomas McNicholas / Nigel Reuel
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Engineering DNA Assembly in Vivo and Knock Down of Gene Expression Using the Reverse Transcriptase Activity

Technology / Case number: #16593
Christopher Voigt / Johann Elbaz
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Diminished Proteolytic Shedding of Receptor Tyrosine Kinases Mediates MEK Inhibitor Resistance in Triple-Negative Breast Cancer

Technology / Case number: #16742
Linda Griffith / Madeleine Oudin / Miles Miller / Aaron Meyer / Frank Gertler / Douglas Lauffenburger
Technology Areas: Therapeutics
Impact Areas: Healthy Living
Labels
  • Women's Health
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High Throughput Isolation of Antigen-Specific Antibodies and Cells

Technology / Case number: #16927J
Jongyoon Han / Galit Alter / Aniruddh Sarkar / Han Wei Hou
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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