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PNA Amphiphile Adjuvant Delivery Vehicles

Technology / Case number: #18878H
Darrell J Irvine / Eric Dane
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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M13 Phage Assembly System for Optimal Blood Trafficking, Tumor Penetration, and Passage Across the Blood Brain Barrier

Technology / Case number: #19438
Angela Belcher / Fred Lam / Uyanga Tsedev
Technology Areas: Drug Delivery / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Open-Ended, Dicer-Cleavable Concatemeric siRNA Generated by Rolling Circle Transcription

Technology / Case number: #18076
Paula Hammond / Kevin Shopsowitz / Connie Wu
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Development of Multi-Specific Antibody-Serum Albumin Fusion Proteins Targeting Multiple Human and Murine CXC (ELR+) Chemokines

Technology / Case number: #19355JQ
Karl Dane Wittrup / Andrew Luster / Alessandro Angelini
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Diazene Directed Modular Synthesis of Oligocyclotryptamines

Technology / Case number: #18747
Mo Movassaghi / Petra Lindovska
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Structured DNA Conjugates

Technology / Case number: #18588
Mark Bathe / Hyungmin Jun / Tyson Shepherd / Remi Veneziano / Sakul Ratanalert
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Synthetic Hybrid Receptor and Genetic Circuit in Probiotic Bacteria to Detect Enteric Pathogenic Microorganisms

Technology / Case number: #17801HJ
James Collins / Douglas Cameron / Ning Mao
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Layer-by-Layer Nanoparticles for Cytokine Therapy in Cancer Treatment

Technology / Case number: #20027H
Darrell J Irvine / Talar Tokatlian / Santiago Correa Echavarria / Antonio Barberio / Mariane Melo / Erik Dreaden / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Methods and Compositions for Increasing Sensitivity of Cancer Cells to Glutaminase Inhibitors and Applications to Cancer Therapy

Technology / Case number: #19305
Matthew Vander Heiden / Laura Danai / Alexander Muir / Dan Gui
Technology Areas: Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Dendrimer Drug Conjugates for Sustained Intra-Articular Delivery

Technology / Case number: #19214
Paula Hammond / Brett Geiger
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Methods for Gene Delivery with Papillomaviruses

Technology / Case number: #21704
Omar Abudayyeh / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Novel Peptidic Agents for Targeting Chemoresistant Anti-Apoptotic Mcl-1

Technology / Case number: #17695J
Amy Keating / Loren Walensky / Greg Bird / Raheleh Rezaei Araghi
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Sensitization of Bacterial Cells to Quinolone Antibiotic by Restoring High Energy Producing Metabolism

Technology / Case number: #20096
James Collins / Arnaud Gutierrez / Michael Lobritz
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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GLYCAN-BINDING PROTEINS AND RELATED COMPOSITIONS AND METHODS

Technology / Case number: #21107
Barbara Imperiali / Elizabeth Ward / Cristina Cella
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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RNA-Based Regulatory Technologies for Improved miRNA Sensors

Technology / Case number: #19686
Ron Weiss / Jin Huh / Kevin Lebo
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Novel Peptidic Agents for Targeting Chemoresistant Anti-Apoptotic Bfl-1

Technology / Case number: #18607
Amy Keating / Justin Jenson
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Mucins as Regulators of Interspecies Microbial Interactions

Technology / Case number: #17408
Katharina Ribbeck / Julia Co / Erica Shapiro / Nicole Kavanaugh
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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Fine-Tuning pKa's of Nucleoside Analogs to Increase Mutagenicity; a Strategy to Develop More Potent Lethal Mutagen with Anti-Viral or Anticancer Properties

Technology / Case number: #17657
John M Essigmann / Sam Peng / Vipender Singh / Bogdan I Fedeles / Andrei Tokmakoff
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers, Advanced Materials
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Designing Universal Influenza Medical Countermeasures

Technology / Case number: #22030L
Darrell Ricke
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Model-based Control for Column-based Continuous Viral Inactivation of Biopharmaceuticals

Technology / Case number: #21959
Richard D Braatz / Moo Sun Hong / Amos Lu
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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