Synthesis of Z-Trifluoromethyl-Substituted Alkenes through Catalytic Cross-Metastasis

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The present disclosure provides compounds, compositions, and methods for preparing alkenyl halides and/or haloalkyl-substituted olefins with Z-selectivity. The methods are particularly useful for preparing alkenyl fluorides such as CF3-substituted olefins by means of cross-metathesis reactions using halogen-containing molybdenum and tungsten complexes.

Researchers

Richard Royce Schrock / Thanch Nguyen / Jakub Hyvl / Ming Koh / Amir Hoveyda

Departments: Department of Chemistry
Technology Areas: Chemicals & Materials: Catalysis & Synthesis
Impact Areas: Advanced Materials

  • halogen-containing metathesis catalysts and methods thereof
    Japan | Granted | 7,011,242
  • halogen-containing metathesis catalysts and methods thereof
    United States of America | Granted | 11,020,730

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