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Medical Treatment Applications of Swellable and Deformable Microspheres

Exclusively Licensed Technology / Case number: #14428J
Elazer R Edelman / Sujata Bhatia / Rinaldo Schiffino / Surbhi Mahajan / Garry Figuly / Tarek Shazly / Michael Feldstein
Technology Areas: Biomaterials & Bioelectronics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Barcoded Combinatorial Genetic Screening with CRISPR-CAS

Exclusively Licensed Technology / Case number: #17251
Timothy K Lu / Ching Gee (Gigi) Choi / Alan Siu Lun Wong
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Engineered Proteins for Targeted Full Spectrum Influenza Neutralization

Exclusively Licensed Technology / Case number: #13937
Ram Sasisekharan / Vidya Subramanian / Venkataramanan Soundararajan / Karthik Viswanathan / Sasisekharan Raguram / Viswanathan Sasisekharan
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Self Actuating Systems for Retention and Electrical Stimulation in the Gastrointestinal Tract

Technology / Case number: #20292JQ
Robert Langer / David Dellal / Ester Caffarel Salvador / Niclas Roxhed / Minsoo Khang / Alex Abramson / Taylor Bensel / Giovanni Traverso
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Solid Formulations with Ultra-High Drug Loading

Technology / Case number: #19446J
Robert Langer / Ester Caffarel Salvador / Niclas Roxhed / Minsoo Khang / Alex Abramson / Taylor Bensel / Giovanni Traverso
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Multi-Pronged Self-Orienting Millimeter-Scale Actuator for Drug Delivery

Technology / Case number: #21169JQ
Robert Langer / Jacob Wainer / Michael Williams / Alex Abramson / Giovanni Traverso
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Self-Righting Systems, Methods, and Related Components

Technology / Case number: #20706JQ
Robert Langer / Ester Caffarel Salvador / Niclas Roxhed / Minsoo Khang / Alex Abramson / Taylor Bensel / Giovanni Traverso
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Using Gamma Wave Oscillation to Reduce Alzheimer's Pathology

Exclusively Licensed Technology / Case number: #18119P
Li-Huei Tsai / Chinnakkaruppan Adaikkan / Anthony Martorell / Hannah Iaccarino / Emery N Brown
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Biomimicry of Immune Tolerance for Universal Transplantation

Exclusively Licensed Technology / Case number: #20985HQJ
Sangeeta Bhatia / Marcela Maus / Arnav Chhabra
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Cyclin-Dependent Kinase 5 (Cdk5) Inhibitory Peptide

Technology / Case number: #19569P
Li-Huei Tsai / Jinsoo Seo
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Glycan-Binding Properties of the 2009 'Swine Flu' H1N1 Influenza A Virus Hemagglutinin and its Mutant Forms

Exclusively Licensed Technology / Case number: #13812
Rahul Raman / Akila Jayaraman / Karthik Viswanathan / Zachary Shriver / Ram Sasisekharan
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Thermostabilization of Dry Lipid Nanoparticle Encapsulating mRNA using Polyvinylpyrrolidone and/or Polyvinyl Alcohol

Exclusively Licensed Technology / Case number: #22963
Robert Langer / John Daristotle / Maria Kanelli / Aurelien Vander Straeten / Morteza Sarmadi / Joseph Collins / Ana Jaklenec
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living

QTY Replacement to Design Water-Soluble Membrane Proteins and Uses Thereof

Exclusively Licensed Technology / Case number: #14760
Alexander Rich / Lotta Tollstoy Tegler / Karolina Corin / Shuguang Zhang
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Large Hydrogel Capsules (>1mm) for Encapsulation of Therapeutic Cells and Cell Aggregates

Exclusively Licensed Technology / Case number: #16104JQ
Robert Langer / Alan Chiu / Omid Veiseh / Joshua Doloff / Delai Chen / Arturo Vegas / Christian Kastrup / Minglin Ma / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials

Strain-Programmable Dressing for Diabetic Wound Healing

Exclusively Licensed Technology / Case number: #22710J
Xuanhe Zhao / Georgios Theocharidis / Aristidis Veves / Heejung Roh / Hyunwoo Yuk
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living

L-SOMA: Oral Delivery of a Biologic Molecule to the Stomach Wall via a Liquid Injection

Technology / Case number: #21194QJ
Robert Langer / Andreas Vegge / Jorrit Jeroen Water / Xiaoya Lu / Mikkel Wennemoes Hvitfeld Ley / Brian Jensen / Mette Poulsen / Jesper Windum / Brian Mouridsen / Mikkel Oliver Jespersen / Morten Frederiksen / Alex Abramson / Giovanni Traverso
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Devices for Needless Drug Delivery in the GI tract

Technology / Case number: #21911QJ
Robert Langer / Adam Jun Bohr / Aghiad Ghazal / Drago Sticker / Cody Cleveland / Torben Sebastia Last / Yi Lu / Graham Arrick / Declan Gwynne / Sean You / Jacob Wainer / Niclas Roxhed / Giovanni Traverso
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Engineered Binding Proteins that Specifically Target Bacteria

Exclusively Licensed Technology / Case number: #22368
Hadley Sikes / Yining Hao / Ki-Joo Sung
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Fanzors are RNA-Guided Nucleases Encoded in Eukaryotic Genomes

Technology / Case number: #24942
Omar Abudayyeh / Kaiyi Jiang / Justin Lim / Jonathan S. Gootenberg
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Compacted Powder Needles for Intramucosal Delivery

Technology / Case number: #21149QJ
Giovanni Traverso / Morten Frederiksen
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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