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An Approach for Enriching the Production of DNA Cargo Loaded AAV5 Capsids in Cells

Technology / Case number: #25585
Paul Barone / Richard D Braatz / Anthony Sinskey / Stacy Springs / Rui Wen Ou / Jacqueline Wolfrum / Prasanna Srinivasan / John Joseph
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Novel Glucose-Responsive Insulin Formulations Using Chemically Modified Insulin Derivatives and Non-Covalent Insulin-Binding Molecules

Technology / Case number: #15976J
Arturo Vegas / Yair Levi / Yunlong Zhang / Benjamin Tang / Hung-Chieh (Danny) Chou / Kun Xue / Matthew Webber / Rosemary Kanasty / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Computer Science / Therapeutics
Impact Areas: Healthy Living
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Machine Learning-Guided Discovery of Nanoparticle Formulations Maximizing mRNA Transfection

Technology / Case number: #25890J
Giovanni Traverso / Ameya Kirtane / Joshua Bernstock / Alvin Chan / Jonathan Woo / Deepak Subramanian / Simon Qu / Xisha Huang / Hao Song / Taksim Ahmed
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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A Computational Method for Identifying the Biophysical Interactions that Determine Human T Cell Specificity from Structural Data and Primary Amino Acid Sequences

Technology / Case number: #26026J
Xingcheng Lin / Herbert Levine / José Onuchic / Ailun Wang / Jason George
Technology Areas: Computer Science / Therapeutics
Impact Areas: Healthy Living
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A Novel Injectable Thiol-Acrylate Poly(ethylene Glycol) Hydrogel for Sustained Release of Methylprednisolone Sodium Succinate

Technology / Case number: #14439J
Eric Woodard / Christopher Pritchard / Daniel Siegwart / Timothy O'Shea / Francis Reynolds / Jonathan Slotkin / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Self Assembled RSV Nanoparticle Vaccines

Technology / Case number: #16549
Vidya Subramanian / Aditya Raguram / Ram Sasisekharan
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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SNAPPLE - Sequencing-Mediated Numerical Analysis of Parallel Proximity Ligation Events

Technology / Case number: #13615B
Andreas Gnirke / Erez Lieberman / Daniel Aird
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Translocation of Non-Natural Chemical Entities Through Anthrax Protective Antigen Pore

Technology / Case number: #15639J
Bradley L. Pentelute / Xiaoli Liao / Amy Rabideau / Jingjing Ling / Gizem Akcay / R. Collier
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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sMutants of Channelrhodopsins with Altered Ion Selectivity

Technology / Case number: #16934TE
Edward Stuart Boyden / Nathan Klapoetke / Amy Chuong / Yongku Cho / Fei Chen
Technology Areas: Electronics & Photonics / Therapeutics
Impact Areas: Healthy Living
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A Novel Multiplexed Inertial Focusing Microfiltration System for Intra-Operative Blood Salvage Autotransfusion

Technology / Case number: #17212DJE
Chwee-Teck Lim / Guofeng Guan / Lidan Wu / Majid Ebrahimi Warkiani / Kah Ping Andy Tay / Jongyoon Han
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Colon Delivery Platform for Constipation Treatment

Technology / Case number: #20570JQ
Giovanni Traverso / Joshua Korzenik / Robert Langer / Christoph Winfried Johannes Steiger
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Ultrasound-Mediated Gastrointestinal Drug Delivery

Technology / Case number: #17807JQ
William Brugge / Avraham Schroeder / Giovanni Traverso / Baris Polat / Carl Schoellhammer / Robert Langer / Daniel Blankschtein
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Mucin-Inspired Glycopolypeptides for Managing Microbial Infections

Technology / Case number: #26189J
Katharina Ribbeck / Kelsey Wheeler / Michaela Gold / Jessica Kramer
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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CD80 is a Biomarker of p53 Activity and a Target for Cancer Therapy

Technology / Case number: #15386H
David Feldser / Leah Schmidt / Tyler Jacks
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Polyamine-Fatty Acid Derived Lipidoids for Drug Delivery

Technology / Case number: #16367
Joseph Dorkin / Owen Fenton / Rebecca McClellan / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Valency Controlled Quantum Dots with Tunable Number of Biotin Binding Sites

Technology / Case number: #12606B
Mark Howarth / Wenhao Liu / Moungi G Bawendi / Alice Ting
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics / Electronics & Photonics / Therapeutics
Impact Areas: Healthy Living
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Methods and Compositions for Protein Labeling Using Lipoic Acid Ligases

Technology / Case number: #12773
Hemanta Baruah / Yoon-Aa Choi / Marta Fernandez Suarez / Alice Ting
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Self-Assembling Peptides Incorporating Modifications and Methods of Use Thereof

Technology / Case number: #13846XE
Yoshiyuki Kumada / Shuguang Zhang
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living
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Polymer Base-Layer for Rapid Delamination of Multi-Layer Films From Microneedles

Technology / Case number: #15346H
Peter DeMuth / Younjin Min / Darrell J Irvine / Paula Hammond
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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A Mitochondria Targeting Platinum(IV) Complex with Dual Cell Killing Modes

Technology / Case number: #13271
Shanta Dhar / Stephen J Lippard
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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