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Biomaterials for Enhanced Implant-Host Integration

Exclusively Licensed Technology / Case number: #22709HJQ
Christopher Chen / Michael Yang / Ritika Chaturvedi / Jan Baranski / Kelly Stevens / Sangeeta Bhatia
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials

Novel RNA Modality for Translation in Eukaryotic Cells

Exclusively Licensed Technology / Case number: #19874Q
Daniel Anderson / Robert Wesselhoeft / Piotr Kowalski
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

SEEDs (in Situ Expansion of Engineered Devices) for Templated Regeneration

Exclusively Licensed Technology / Case number: #18069HJQ
Christopher Chen / Kelly Stevens / Sangeeta Bhatia
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living

Shear-thinning Injectable Hydrogels for Multi-stage Drug Delivery

Exclusively Licensed Technology / Case number: #16764
Robert Langer / Mark Tibbitt / Eric Appel
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

Devices and Methods for Non-Invasive Hematological Measurements

Exclusively Licensed Technology / Case number: #18366J
Maria Jesus Ledesma Carbayo / Tom Vettenburg / Alberto Pablo Trinidad / Jason Tucker-Schwartz / Luis Soenksen Martinez / Aurelien Bourquard / Carlos Castro Gonzalez / Ian Butterworth / Alvaro Sanchez Ferro
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living

Body Fluid Resistant Tissue Glues

Exclusively Licensed Technology / Case number: #21933J
Xuanhe Zhao / Christoph Nabzdyk / Xinyu Mao / Hyunwoo Yuk
Technology Areas: Biomaterials & Bioelectronics / Therapeutics
Impact Areas: Healthy Living, Advanced Materials

In Situ Curing Hydrophobic Tissue Adhesive

Exclusively Licensed Technology / Case number: #16181J
Robert Langer / Yuhan Lee / Nora Lang / Maria Jose Pereira / Pedro Del Nido / Jeffrey Michael Karp
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials

Lipomer Nanoparticles for Highly Efficient SiRNA Delivery

Exclusively Licensed Technology / Case number: #14649
Robert Langer / James Dahlman / Avraham Schroeder / Christopher Levins / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Peripheral Neural Interface via Nerve Regeneration to Distal Tissues

Exclusively Licensed Technology / Case number: #16650TE
Hugh M Herr / Matthew Carty / Rick Casler / Ronald Riso / Katherine Song
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living

SAR of Bromodomain Inhibitor/Linker for Modulation of Release Profile of BET-BRUSH Prodrugs

Exclusively Licensed Technology / Case number: #20376
Jeremiah A. Johnson / Farrukh Vohidov
Technology Areas: Therapeutics
Impact Areas: Healthy Living

Broad Neutralizing Antibodies to Groups 1 and 2 Influenza HA

Exclusively Licensed Technology / Case number: #15049
Ram Sasisekharan / Vidya Subramanian / Kannan Tharakaraman / Venkataramanan Soundararajan / Sasisekharan Raguram / Viswanathan Sasisekharan
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Modified Alginates for Islet Encapsulation and Diabetes Treatment

Exclusively Licensed Technology / Case number: #14528JQ
Robert Langer / Arturo Vegas / Kaitlin Bratlie / Minglin Ma / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials

Lipid/Polymer Nanoformulations with Alphavirus Replicon RNA

Exclusively Licensed Technology / Case number: #17996H
Darrell J Irvine / Yuan Zhang / Mariane Melo / Tasuku Kitada / Ron Weiss
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Modified Alginates for Use as Anti-Fibrotic Materials

Exclusively Licensed Technology / Case number: #16906JQ
Robert Langer / Omid Veiseh / Joshua Doloff / Arturo Vegas / Minglin Ma / Daniel Anderson
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials

End-to-End Machine Learning-Driven Design of Targeted Monoclonal Antibodies

Exclusively Licensed Technology / Case number: #24595L
Matthew Walsh / Rajmonda Caceres / Rafael Jaimes / Lin Li / Esther Wolf / Will Spaeth / Leslie Shing / Tristan Bepler
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

Modified Alginates for Anti-Fibrotic Materials and Applications

Exclusively Licensed Technology / Case number: #21323JQ
Robert Langer / Omid Veiseh / Joshua Doloff / Arturo Vegas / Minglin Ma / Daniel Anderson
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living

Natural Evolution of H5N1 Hemagglutinin Amino Acid Sequence and Its Implication on Human Adaptation and Antigenicity

Exclusively Licensed Technology / Case number: #16072
Rahul Raman / Nathan Stebbins / Kannan Tharakaraman / Karthik Viswanathan / Ram Sasisekharan
Technology Areas: Diagnostics / Therapeutics

Medical Treatment Applications of Swellable and Deformable Microspheres

Exclusively Licensed Technology / Case number: #14428J
Elazer R Edelman / Sujata Bhatia / Rinaldo Schiffino / Surbhi Mahajan / Garry Figuly / Tarek Shazly / Michael Feldstein
Technology Areas: Biomaterials & Bioelectronics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living

Barcoded Combinatorial Genetic Screening with CRISPR-CAS

Exclusively Licensed Technology / Case number: #17251
Timothy K Lu / Ching Gee (Gigi) Choi / Alan Siu Lun Wong
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living

Engineered Proteins for Targeted Full Spectrum Influenza Neutralization

Exclusively Licensed Technology / Case number: #13937
Ram Sasisekharan / Vidya Subramanian / Venkataramanan Soundararajan / Karthik Viswanathan / Sasisekharan Raguram / Viswanathan Sasisekharan
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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