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Biodegradable Lipid-Like Materials for Applications in siRNA Delivery

Technology / Case number: #15420
Kathryn Whitehead / Arturo Vegas / Yunlong Zhang / Joseph Dorkin / Robert Langer / Daniel Anderson
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Self- Regulated Peptide Hydrogel for Closed Loop Insulin Delivery

Technology / Case number: #15056J
Zhen Gu / Alex Aimetti / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Biodegradable Polyamine-Fatty Acid Derived Lipidoids for Drug Delivery

Technology / Case number: #16367
Joseph Dorkin / Owen Fenton / Rebecca McClellan / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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1,2-Aminoalcohol Lipidoids (II)

Technology / Case number: #13661Q
Kerry Mahon / Kevin Love / Christopher Levins / Kathryn Whitehead / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Methods for Increasing Safety of Embryonic Stem Cells

Technology / Case number: #13769
Jeffrey Millman / Clark Colton
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Formulation of Polymeric Particles for Prostate Cancer Targeting

Technology / Case number: #12162J
Jianjun Cheng / Benjamin Teply / Stephen Zale / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Immune Pharmacytes: Nanoparticle-Modified Leukocytes for Immunotherapy

Technology / Case number: #13509H
Matthias Stephan / Jae Hyun (James) Moon / Anna Bershteyn / Darrell J Irvine
Technology Areas: Diagnostics / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Lithium-Ion Fiber Battery

Technology / Case number: #16676
Benjamin Grena / Yoel Fink
Technology Areas: Chemicals & Materials / Drug Delivery / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
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Extended Transient Transfection by Repeated Delivery of RNA

Technology / Case number: #13415
Matthew Angel / Mehmet Yanik
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Surface Binding of Nanoparticles-Based Drug Delivery to Tissue

Technology / Case number: #15731
Rohit N Karnik / Cliff Wong / Ambika Bajpayee / Alan Grodzinsky / Moungi G Bawendi
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Nanoparticle Technology for Immune Response Against Small and Macromolecules-Method of Preparation and Uses Thereof

Technology / Case number: #13399J
Frank Alexis / Pamela Basto / Ulrich Von Andrian / Elliot Moseman / Matteo Iannacone / Jinjun Shi / Elena Tonti / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Polymer Brush-Poly(glycoamidoamine)-Lipids (PGAL) and Uses Thereof

Technology / Case number: #15942
Yizhou Dong / Joseph Dorkin / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Engineering Microbes and Metabolic Pathways for the Production of Ethylene Glycol from Xylose, Glucose, Carbohydrates and Renewable Resources

Technology / Case number: #15064
Deepak Dugar / Brian Pereira / Marjan De Mey / Jose Avalos / Gregory Stephanopoulos
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Vaccine Nanotechnology and Uses Thereof

Technology / Case number: #12788J
Frank Alexis / Liangfang Zhang / Pamela Basto / Ulrich Von Andrian / Tobias Junt / Elliot Moseman / Matteo Iannacone / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Zwitterionic Dopamine Sulfonate Coated Iron Oxide Nanoparticles

Technology / Case number: #15322
Numpon Insin / Hee-Sun Han / He Wei / Moungi G Bawendi
Technology Areas: Chemicals & Materials / Drug Delivery / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Cellular Surface Engineering via Multilayered Polymer Nanostructures

Technology / Case number: #12846
Albert Swiston / Michael F Rubner / Robert Cohen / Darrell J Irvine
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Ultrasonic Method for Measuring Concentrations of Particles, Cells and Islets in Suspension

Technology / Case number: #11886J
Steven Africk / Clark Colton
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
License

Method for Modulating the Immune System Using Adjuvant-Loaded Nanoparticle-Bacteria Constructs

Technology / Case number: #16067J
Michael Starnbach / Aleksandar Radovic-Moreno / Pamela Basto / Ulrich Von Andrian / Georg Stary / Robert Langer / Omid Farokhzad
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
License

Nanoparticle Delivery of Adjuvant-Method of Preparation and Uses Thereof

Technology / Case number: #13344J
Frank Alexis / Pamela Basto / Ulrich Von Andrian / Elliot Moseman / Matteo Iannacone / Jinjun Shi / Elena Tonti / Robert Langer / Omid Farokhzad
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Thiol-yne Mediated Synthesis of Multi-Tailed Lipids for siRNA Delivery

Technology / Case number: #15846
Kevin Love / Akinleye Alabi / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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